公开(公告)号：US20080227746A1

公开(公告)日：2008-09-18

申请号：US11630049

申请日：2005-06-17

申请人： Gerry Boss ,  Vijay Sharama ,  Kate E. Broderick

发明人： Gerry Boss ,  Vijay Sharama ,  Kate E. Broderick

IPC分类号： A61K31/714 ,  A61K31/555 ,  C07F15/06 ,  A61P1/16

CPC分类号： A61K31/70

摘要： Methods for treating disease states in a subject caused or exacerbated by the presence of excess nitric oxide (NO) or excess cyanide are provided. Methods for alleviating the symptoms of a disease state in a subject caused or exacerbated by the presence of excess nitric oxide (NO) or excess cyanide in the subject are also provided. Pharmaceutical compositions comprising cobinamide and a pharmaceutically acceptable carrier are also provided.

摘要翻译： 提供了通过过量一氧化氮（NO）或过量氰化物的存在来治疗受试者的疾病状态引起或加剧的方法。 还提供了减轻受试者中过量一氧化氮（NO）或过量氰化物的存在引起或加剧的受试者疾病状态症状的方法。 还提供了包含联苯胺酰胺和药学上可接受的载体的药物组合物。