公开(公告)号：US20150038505A1

公开(公告)日：2015-02-05

申请号：US14446011

申请日：2014-07-29

Applicant: Gilead Connecticut, Inc.

Inventor： Tim G. ELFORD ,  Peter Chee-Chu FUNG ,  Michael Laird HURREY ,  Dimitrios STEFANIDIS ,  Dragos VIZITIU

IPC: C07D487/04 ,  C07C309/04

CPC classification number: C07D487/04 ,  C07C309/04

Abstract: Polymorphs of a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, are provided. The bis-mesylate salt may also be depicted as a compound of Formula IA: Provided herein are also compositions thereof, methods for their preparation and methods for such polymorphs.

Abstract translation: 提供了式I化合物的双甲磺酸盐或其水合物的多晶型物。 双甲磺酸盐也可以描述为式IA的化合物：本文还提供其组合物，其制备方法和这些多晶型物的方法。