公开(公告)号：US20130338142A1

公开(公告)日：2013-12-19

申请号：US13918848

申请日：2013-06-14

Applicant: Gilead Connecticut, Inc.

Inventor： Peter A. BLOMGREN ,  Kevin S. CURRIE ,  Randall HALCOMB ,  Jeffrey E. KROPF ,  Seung H. LEE ,  Jiayao LI ,  Jennifer R. LO ,  Scott A. MITCHELL ,  Aaron SCHMITT ,  Qiaoyin WU ,  Jin-Min XIONG ,  Jianjun XU ,  Zhongdong ZHAO ,  Jayaraman CHANDRASEKHAR ,  Eric LANSDON

IPC: C07D487/04 ,  C07D498/10 ,  C07D513/04 ,  C07D498/04

CPC classification number: C07D487/04 ,  C07D498/04 ,  C07D498/10 ,  C07D513/04 ,  C07D519/00

Abstract: Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of an imidazopyrazine compound effective to reduce signs or symptoms of the disease or disorder are provided.

Abstract translation: 本文提供了某些咪唑并嗪及其药物组合物。 治疗患有对抑制Syk活性有反应的某些疾病和病症的患者的方法，其包括给予这些患者一定量的有效减少疾病或病症的体征或症状的咪唑并吡嗪化合物。