公开(公告)号：US10354748B1

公开(公告)日：2019-07-16

申请号：US14671167

申请日：2015-03-27

Applicant: Google Inc.

Inventor： David Konerding ,  Jeffrey Adgate Dean ,  Sanjay Ghemawat ,  Jonathan Bingham

IPC: G16B50/00 ,  G06F16/13 ,  G06F16/28 ,  G06F16/174

Abstract: A method includes receiving, by a processing device, a plurality of genome files. Each genome file corresponds to a different sample and defining a genetic sequence. The method also includes generating, by the processing device, a two-dimensional alignment file based on the genome files and a reference sequence. A first dimension of the alignment file corresponds to individual genetic sequences and each of the genetic sequences is aligned with respect to the reference sequence along a second dimension of the alignment file. The method includes separating, by the processing device, the alignment file into a plurality of groups and storing the groups in a non-transitory genome data store. Each group contains segments of the genetic sequences of two or more of the genomic files.

公开(公告)号：US10720231B1

公开(公告)日：2020-07-21

申请号：US15690844

申请日：2017-08-30

Applicant: Google Inc.

Inventor： David Konerding ,  Jeffrey Adgate Dean ,  Sanjay Ghemawat ,  Jonathan Bingham

IPC: G16B50/00 ,  G06F16/13 ,  G06F16/28 ,  G06F16/174

Abstract: A method includes receiving, by a processing device, a plurality of genome files. Each genome file corresponds to a different sample and defining a genetic sequence. The method also includes generating, by the processing device, a two-dimensional alignment file based on the genome files and a reference sequence. A first dimension of the alignment file corresponds to individual genetic sequences and each of the genetic sequences is aligned with respect to the reference sequence along a second dimension of the alignment file. The method includes separating, by the processing device, the alignment file into a plurality of groups and storing the groups in a non-transitory genome data store. Each group contains segments of the genetic sequences of two or more of the genomic files.