公开(公告)号：US08280125B2

公开(公告)日：2012-10-02

申请号：US12012385

申请日：2008-02-01

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jarek Rossignac

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jarek Rossignac

IPC分类号： G06K9/00

CPC分类号： G06T7/149 ,  G06T7/11 ,  G06T2207/30101

摘要： A method and system for segmenting tubular or stroke-like structures in 2D images is disclosed. Examples of such structures include, but are not limited to, blood vessels, bones, roads, rivers, electrical wirings, and brush-strokes. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are 2D disks, each having a center location and a radius determined based on local pixel intensities in the image. A continuous model of the tubular structure is generated by interpolating the center locations and radii of the ordered series of pearls.

摘要翻译： 公开了一种用于在2D图像中分割管状或笔触状结构的方法和系统。 这种结构的实例包括但不限于血管，骨骼，道路，河流，电气布线和笔触。 接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。 基于该信息，沿管状结构产生有序的珍珠系列。 珍珠是2D盘，每个盘具有基于图像中的局部像素强度确定的中心位置和半径。 通过内插有序系列珍珠的中心位置和半径来产生管状结构的连续模型。

公开(公告)号：US08218910B2

公开(公告)日：2012-07-10

申请号：US12413913

申请日：2009-03-30

申请人： Gregory G. Slabaugh ,  Jaroslaw Rossignac ,  Brian Whited ,  Tong Fang ,  Gozde Unal

发明人： Gregory G. Slabaugh ,  Jaroslaw Rossignac ,  Brian Whited ,  Tong Fang ,  Gozde Unal

IPC分类号： G06K9/32

CPC分类号： G06T17/10

摘要： A method of computing a continuous interpolation of a discrete set of three-dimensional (3D) balls, including generating an initial skin, wherein the initial skin is a surface comprised of splines and wherein the splines touch each ball along a circle that is tangent to the ball, solving a first differential equation to minimize the initial skin's surface area or solving a second differential equation to minimize a squared mean curvature of the initial skin's surface, wherein the result of solving the first or second differential equations is an updated skin; and repeating the steps of solving the first or second differential equations for the updated skin, and then, repeating the steps of solving the first or second differential equations for each subsequently updated skin until a desired skin is realized.

摘要翻译： 一种计算三维（3D）球的离散组的连续插值的方法，包括生成初始皮肤，其中所述初始皮肤是由样条线组成的表面，并且其中所述花键沿着与所述三维 球，解决第一微分方程以最小化初始皮肤的表面积或求解第二微分方程以最小化初始皮肤表面的平均平均曲率，其中求解第一或第二微分方程的结果是更新的皮肤; 并且重复解决用于更新的皮肤的第一或第二微分方程的步骤，然后重复以下步骤：为每个随后更新的皮肤求解第一或第二微分方程，直到实现期望的皮肤。

公开(公告)号：US07957591B2

公开(公告)日：2011-06-07

申请号：US11538849

申请日：2006-10-05

申请人： Gozde Unal ,  Bertrand Peny ,  Gregory G. Slabaugh ,  Christopher Alvino ,  Tong Fang

发明人： Gozde Unal ,  Bertrand Peny ,  Gregory G. Slabaugh ,  Christopher Alvino ,  Tong Fang

IPC分类号： G06K9/34

CPC分类号： G06T7/11 ,  G06T2207/10072 ,  G06T2207/20104 ,  G06T2207/20156 ,  G06T2207/30096

摘要： Disclosed is a method and system for propagating information about an image to segment a target structure. An input to denote a region of interest of the image containing the target structure is received. A first seed is set outside of the target structure and a second seed is set inside the target structure. A first partial differential equation (PDE) associated with the first seed is solved and a second PDE associated with the second seed is solved to segment the image.

摘要翻译： 公开了一种用于传播关于图像的信息以分割目标结构的方法和系统。 接收用于表示包含目标结构的图像的感兴趣区域的输入。 将第一种子设置在目标结构之外，并且将第二种子设置在目标结构内。 解决与第一种子相关联的第一偏微分方程（PDE），并且解决与第二种子相关联的第二PDE以分割图像。

公开(公告)号：US07831078B2

公开(公告)日：2010-11-09

申请号：US11779413

申请日：2007-07-18

申请人： Gozde Unal ,  Susann Bucher ,  Gregory G. Slabaugh ,  Tong Fang

发明人： Gozde Unal ,  Susann Bucher ,  Gregory G. Slabaugh ,  Tong Fang

IPC分类号： G06K9/00

CPC分类号： G06K9/621 ,  G06K2209/05 ,  G06T7/12 ,  G06T7/149 ,  G06T7/174 ,  G06T2207/10081 ,  G06T2207/10132 ,  G06T2207/30101 ,  Y10S128/922

摘要： A method for segmenting intravascular images includes acquiring a series of digitized images acquired from inside a vessel, each said image comprising a plurality of intensities corresponding to a 2-dimensional grid of pixels, providing a precomputed set of shapes for modeling contours of vessel wall boundaries, wherein a contour can be expressed as a sum of a mean shape and a inner product of shape modes and shape weights, initializing a boundary contour for one of said set of images, initializing said shape weights by projecting a contour into said shape modes, updating said shape weights from differential equations of said shape weights, and computing a contour by summing said mean shape and said inner product of shape modes and updated shape weights.

摘要翻译： 用于分割血管内图像的方法包括获取从血管内获取的一系列数字化图像，每个所述图像包括对应于像素的二维网格的多个强度，提供用于建模血管壁边界的轮廓的预先计算的一组形状 其中轮廓可以表示为平均形状和形状模式和形状权重的内积的和，初始化所述图像集合中的一个图像的边界轮廓，通过将轮廓投影到所述形状模式中来初始化所述形状权重， 从所述形状权重的微分方程更新所述形状权重，以及通过将所述平均形状和形状模式的内积与更新的形状权重相加来计算轮廓。

公开(公告)号：US20080260221A1

公开(公告)日：2008-10-23

申请号：US12045327

申请日：2008-03-10

申请人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang ,  Shawn Linkton ,  Valer Canda ,  Stefan Thesen ,  Shuping Qing

发明人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang ,  Shawn Linkton ,  Valer Canda ,  Stefan Thesen ,  Shuping Qing

IPC分类号： G06K9/00

CPC分类号： G06K9/6207 ,  G06F19/00 ,  G06K9/342 ,  G06K2009/366 ,  G06K2209/053 ,  G06T7/12 ,  G06T7/149 ,  G06T7/194 ,  G06T2200/04 ,  G06T2207/10088 ,  G06T2207/20104 ,  G06T2207/30096

摘要： A method for lesion segmentation in 3-dimensional (3D) digital images, includes selecting a 2D region of interest (ROI) from a 3D image, the ROI containing a suspected lesion, extending borders of the ROI to 3D forming a volume of interest (VOI), where voxels on the borders of the VOI are initialized as background voxels and voxels in an interior of the VOI are initialized as foreground voxels, propagating a foreground and background voxel competition where for each voxel in the VOI, having each neighbor voxel in a neighborhood of the voxel attack the voxel, and, if the attack is successful, updating a label and strength of the voxel with that of the successful attacking voxel, and evolving a surface between the foreground and background voxels in 3D until an energy functional associated with the surface converges in value, where the surface segments the suspected lesion from the image.

摘要翻译： 一种用于三维（3D）数字图像中的病变分割的方法，包括从3D图像中选择感兴趣的2D区域（ROI），ROI包含疑似病变，将ROI的边界延伸到形成感兴趣体积的3D（ VOI），其中VOI边界上的体元被初始化为背景体元素，并且VOI内部的体素被初始化为前景体素，传播前景和背景体素竞争，其中对于VOI中的每个体素，具有每个相邻体素 体素的邻域攻击体素，并且如果攻击成功，更新体素的标签和强度与成功的攻击体素的标记和强度，并且以3D形式在前景和背景体素之间演变出一个表面，直到能量功能相关 其表面收敛于值，其中表面将图像中的可疑病变分割。

公开(公告)号：US08290247B2

公开(公告)日：2012-10-16

申请号：US12150817

申请日：2008-05-01

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jaroslaw Rossignac

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jaroslaw Rossignac

IPC分类号： G06K9/00

CPC分类号： G06K9/342 ,  G06T7/11 ,  G06T2200/04 ,  G06T2207/10072 ,  G06T2207/20101 ,  G06T2207/30101

摘要： A method and system for segmenting tubular structures in 3D images is disclosed. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are spheres, each having a center location and a radius determined based on the center locations and radii of previous pearls and on local voxel intensities in the image. A continuous model of the tubular structure can be generated by interpolating the center locations and radii of the ordered series of pearls. The ordered series of pearls can be displayed and easily edited in response to user input, thus providing an efficient and flexible method for interactive segmentation of a potion of interest in a tubular structure.

摘要翻译： 公开了一种用于在3D图像中分割管状结构的方法和系统。 接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。 基于该信息，沿着管状结构产生有序的珍珠系列。 珍珠是球体，每个球体具有基于中心位置和先前珍珠的半径确定的中心位置和半径以及图像中的局部体素强度。 可以通过内插有序系列珍珠的中心位置和半径来生成管状结构的连续模型。 可以根据用户输入显示和容易地编辑有序的珍珠系列，从而为管状结构中感兴趣的药水进行交互式分割提供了一种有效和灵活的方法。

公开(公告)号：US08069022B2

公开(公告)日：2011-11-29

申请号：US11465628

申请日：2006-08-18

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

IPC分类号： G06G17/50 ,  G06G7/48 ,  H04R25/00

CPC分类号： G06K9/6206 ,  H04R25/652 ,  H04R25/658 ,  H04R2225/77

摘要： A method and apparatus is disclosed whereby a point on an ear impression model to be labeled is selected and a shape context is determined for that point. This shape context is then compared to average shape contexts for different regions on a reference ear impression model, also referred to herein as an ear impression shape atlas. A cost function is used to determine the minimum cost between the shape context for the selected point and one of the average shape contexts. Once the minimized cost is determined, the region label corresponding to the average shape context having a minimized cost is assigned to that point. In this way, points on the surface of an ear impression are classified and labeled as being located in regions corresponding to the regions on the ear impression shape atlas.

摘要翻译： 公开了一种方法和装置，由此选择要标记的耳朵印象模型上的点，并且为该点确定形状上下文。 然后将该形状上下文与参考耳部印象模型上的不同区域的平均形状上下文进行比较，这里也称为耳朵印象形状图集。 成本函数用于确定所选点的形状上下文与平均形状上下文之间的最小成本。 一旦确定了最小化成本，则将具有最小化成本的平均形状上下文对应的区域标签分配给该点。 以这种方式，将耳朵表面的点分类并标记为位于与耳朵印象形状图集上的区域对应的区域中。

公开(公告)号：US08005652B2

公开(公告)日：2011-08-23

申请号：US11466149

申请日：2006-08-22

申请人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang

发明人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang

IPC分类号： G06F7/60 ,  G06F17/50

CPC分类号： H04R25/658 ,  G06K9/469 ,  H04R25/652 ,  H04R2225/77

摘要： An improved method of designing hearing aid molds is disclosed whereby regions of an ear impression model are identified as a function of a geodesic distance measure. According to a first embodiment, a canal point of an ear impression model is identified as that point having a maximum normalized geodesic distance as compared to all other points on the surface of the ear impression model. According to a second embodiment, a helix point of the ear impression model is identified as that point having a maximum normalized geodesic distance as compared to all points except those points in the canal region of the ear impression model. Finally, in accordance with another embodiment, a geodesic distance between a canal point and a helix point of an ear impression model is identified and a percentage threshold, illustratively 65%, is applied to that geodesic distance to identify a crus region.

摘要翻译： 公开了一种改进的助听器模具的设计方法，其中耳朵印模模型的区域被识别为测地距离测量的函数。 根据第一实施例，与耳朵印象模型的表面上的所有其他点相比，耳朵印模模型的运河点被识别为具有最大归一化测地距离的点。 根据第二实施例，与除了耳朵模型的运河区域中的那些点之外的所有点相比，耳朵印模模型的螺旋点被识别为具有最大归一化测地距离的点。 最后，根据另一个实施例，识别耳朵印模模型的运河点和螺旋点之间的测地距离，并且示例性地将65％的百分比阈值应用于该测地距离以识别小腿区域。

公开(公告)号：US07961944B2

公开(公告)日：2011-06-14

申请号：US11933516

申请日：2007-11-01

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

IPC分类号： G06K9/34

CPC分类号： G06T17/10

摘要： A method for modeling a 2-dimensional tubular structure in a digitized image includes providing a digitized image of a tubular structure containing a plurality of 2D balls of differing radii, initializing a plurality of connected spline segments that form an envelope surrounding the plurality of 2D balls, each the spline segment Si being parameterized by positions of the ith and i+1th balls and contact angles αi, αi+1 from the center of each respective ball to a point on the perimeter of each the ball contacting the spline segment Si, each the αi affecting spline segment Si and Si−1, and updating the angles by minimizing an energy that is a functional of the angles, where the updating is repeated until the energy is minimized subject to a constraint that the envelope is tangent to each ball at each point of contact, where the envelope is represented by the contact angles.

摘要翻译： 一种用于对数字化图像中的二维管状结构进行建模的方法包括提供包含不同半径的多个2D球的管状结构的数字化图像，初始化形成围绕多个2D球的包围的多个连接的花键片段 每个花键片段Si由第i和第i + 1个球的位置参数化，接触角αi，αi+ 1从每个相应球的中心到接触花键片段Si的每个球的周边上的点，每个 αi影响样条段Si和Si-1，并且通过使作为角度的函数的能量最小化来更新角度，其中重复更新直到能量被最小化，受限于包围与每个球相切的约束 每个接触点，其中信封由接触角表示。

公开(公告)号：US20090016588A1

公开(公告)日：2009-01-15

申请号：US12150817

申请日：2008-05-01

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jaroslaw Rossignac

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jaroslaw Rossignac

IPC分类号： G06K9/34

CPC分类号： G06K9/342 ,  G06T7/11 ,  G06T2200/04 ,  G06T2207/10072 ,  G06T2207/20101 ,  G06T2207/30101

摘要： A method and system for segmenting tubular structures in 3D images is disclosed. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are spheres, each having a center location and a radius determined based on the center locations and radii of previous pearls and on local voxel intensities in the image. A continuous model of the tubular structure can be generated by interpolating the center locations and radii of the ordered series of pearls. The ordered series of pearls can be displayed and easily edited in response to user input, thus providing an efficient and flexible method for interactive segmentation of a potion of interest in a tubular structure.

摘要翻译： 公开了一种用于在3D图像中分割管状结构的方法和系统。 接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。 基于该信息，沿管状结构产生有序的珍珠系列。 珍珠是球体，每个球体具有基于中心位置和先前珍珠的半径确定的中心位置和半径以及图像中的局部体素强度。 可以通过内插有序系列珍珠的中心位置和半径来生成管状结构的连续模型。 可以根据用户输入显示和容易地编辑有序的珍珠系列，从而为管状结构中感兴趣的药水进行交互式分割提供了一种有效和灵活的方法。