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公开(公告)号：US09486651B2
公开(公告)日：2016-11-08
申请号：US12531495
申请日：2008-03-07
CPC分类号： A61N7/02 , A61B90/39 , A61B2090/374 , A61B2090/376 , A61N5/1049 , A61N2005/1061
摘要： The present disclosure provides for effective systems and methods for increasing target tissue conspicuity within a particular anatomy of a particular patient. In an exemplary embodiment, a system associated with the present disclosure includes: (a) a MRI-guided HIFU system for generating ablation markings on a target tissue region, the MRI-guided HIFU system including a transducer for delivering HIFU to the target tissue region, the delivered HIFU generating the ablation markings on the target tissue and an MRI imaging system adapted to generate a three dimensional image of the target tissue region during HIFU delivery for guiding the delivery of the HIFU to the target tissue region; (b) a radiotherapy delivery system for delivering radiotherapy treatment to the target tissue region; and (c) a CT imaging system operable within the radiotherapy delivery system for generating a three dimensional image of the target tissue region. The markings generated on the target tissue region by the MRI-guided HIFU are visible in the image generated by the CT imaging system. The image generated by the CT imaging system guides the location of the radiotherapy treatment delivered to the target tissue region.
摘要翻译： 本公开提供了用于增加特定患者的特定解剖结构内的目标组织显着性的有效系统和方法。 在示例性实施例中，与本公开相关联的系统包括：（a）用于在目标组织区域上产生消融标记的MRI引导的HIFU系统，所述MRI引导的HIFU系统包括用于将HIFU传送到目标组织区域的换能器 所传送的HIFU在靶组织上产生消融标记，以及MRI成像系统，其适于在HIFU递送期间产生目标组织区域的三维图像，用于将HIFU传送到目标组织区域; （b）放射治疗递送系统，用于向目标组织区域递送放射治疗; 和（c）可在放射治疗递送系统内操作的用于产生目标组织区域的三维图像的CT成像系统。 通过MRI引导的HIFU在靶组织区域上产生的标记在CT成像系统产生的图像中是可见的。 由CT成像系统产生的图像引导放射治疗治疗传送到目标组织区域的位置。
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2.发明申请公开(公告)号：US20100106005A1
公开(公告)日：2010-04-29
申请号：US12531495
申请日：2008-03-07
CPC分类号： A61N7/02 , A61B90/39 , A61B2090/374 , A61B2090/376 , A61N5/1049 , A61N2005/1061
摘要： The present disclosure provides for effective systems and methods for increasing target tissue conspicuity within a particular anatomy of a particular patient. In an exemplary embodiment, a system associated with the present disclosure includes: (a) a MRI-guided HIFU system for generating ablation markings on a target tissue region, the MRI-guided HIFU system including a transducer for delivering HIFU to the target tissue region, the delivered HIFU generating the ablation markings on the target tissue and an MRI imaging system adapted to generate a three dimensional image of the target tissue region during HIFU delivery for guiding the delivery of the HIFU to the target tissue region; (b) a radiotherapy delivery system for delivering radiotherapy treatment to the target tissue region; and (c) a CT imaging system operable within the radiotherapy delivery system for generating a three dimensional image of the target tissue region. The markings generated on the target tissue region by the MRI-guided HIFU are visible in the image generated by the CT imaging system. The image generated by the CT imaging system guides the location of the radiotherapy treatment delivered to the target tissue region.
摘要翻译： 本公开提供了用于增加特定患者的特定解剖结构内的目标组织显着性的有效系统和方法。 在示例性实施例中，与本公开相关联的系统包括：（a）用于在目标组织区域上产生消融标记的MRI引导的HIFU系统，所述MRI引导的HIFU系统包括用于将HIFU传送到目标组织区域的换能器 所传送的HIFU在靶组织上产生消融标记，以及MRI成像系统，其适于在HIFU递送期间产生目标组织区域的三维图像，用于将HIFU传送到目标组织区域; （b）放射治疗递送系统，用于向目标组织区域递送放射治疗; 和（c）可在放射治疗递送系统内操作的用于产生目标组织区域的三维图像的CT成像系统。 通过MRI引导的HIFU在靶组织区域上产生的标记在CT成像系统产生的图像中是可见的。 由CT成像系统产生的图像引导放射治疗治疗传送到目标组织区域的位置。
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3.发明授权Means to correlate images from scans taken at different times including means to determine the minimum distances between a patient anatomical contour and a correlating surface 失效用于将在不同时间拍摄的扫描图像相关联的手段，包括确定患者解剖轮廓和相关表面之间的最小距离的装置
公开(公告)号：US4977505A
公开(公告)日：1990-12-11
申请号：US198043
申请日：1988-05-24
IPC分类号： G06T5/00
CPC分类号： G06T5/006
摘要： Herein is described a method for creating composite images from disparate sets of tomographic images. The images may be derived from CAT, MRI or PET systems. Initially, a "head" is created from one set of tomographic image slices. The head comprises a three dimensional stack of contours created from such slices. A "hat" is created from another set of tomographic image slices with the hat being described by a plurality of points with coordinate positions which define the three dimensional surface of stack of image slices. The hat is then superimposed over the head and subsequently, a determination is made by examination of side and top planar views of the hat and head, of a factor which defines the mean distance of the hat points from the head contours. The hat is subsequently adjusted relative to the head until the mean distance is found to be within minimum limits.
摘要翻译： 这里描述了用于从不同的断层图像集合创建合成图像的方法。 图像可以来自CAT，MRI或PET系统。 最初，从一组断层图像切片创建“头部”。 头部包括由这种切片形成的三维轮廓。 由另一组断层图像切片创建“帽子”，其中帽子由具有定义图像切片堆叠的三维表面的坐标位置的多个点描述。 然后将帽子叠加在头部上，随后通过检查帽子和头部的侧面和顶部平面视图来确定帽子点与头部轮廓的平均距离的因子。 帽子随后相对于头部进行调整，直到发现平均距离处于最小限度内。
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公开(公告)号：US07265356B2
公开(公告)日：2007-09-04
申请号：US10998509
申请日：2004-11-29
IPC分类号： G01T1/24
CPC分类号： G01T1/1641 , A61N5/1049 , A61N5/1065 , A61N2005/1052 , A61N2005/1061 , G01T1/166
摘要： In some embodiments, an image-guided radiotherapy apparatus and method is provided in which a radiotherapy radiation source and a gamma ray photon imaging device are positioned with respect to a patient area so that a patient can be treated by a beam emitted from the radiotherapy apparatus and can have images taken by the gamma ray photon imaging device. Radiotherapy treatment and imaging can be performed substantially simultaneously and/or can be performed without moving the patient in some embodiments. The gamma ray photon imaging device can be coupled and movable with respect to any part of a building structure, can be located on a portable frame movable to and from the radiotherapy radiation source and patient, or can take other forms. In some embodiments, the gamma ray photon imaging device can be used for imaging in connection with other types of medical interventions.
摘要翻译： 在一些实施例中，提供了一种图像引导放射治疗装置和方法，其中放射治疗辐射源和伽马射线光子成像装置相对于患者区域定位，使得可以通过从放射治疗装置发射的束来对患者进行治疗 并且可以具有由伽马射线光子成像装置拍摄的图像。 在一些实施例中，放射治疗和成像可以基本上同时进行和/或执行而不移动患者。 伽马射线光子成像装置可以相对于建筑结构的任何部分联接和移动，可以位于可移动到放射治疗辐射源和患者的便携式框架上，或者可以采取其他形式。 在一些实施例中，伽马射线光子成像装置可用于与其他类型的医疗干预相结合的成像。
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