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1.发明申请PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES 有权制备4-氨基-5-氟-3-羟基-6-（取代的）吡啶甲酸酯的方法公开(公告)号：US20120190860A1
公开(公告)日：2012-07-26
申请号：US13356691
申请日：2012-01-24
申请人： Gregory T. Whiteker , Kim E. Arndt , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary A. Roth , Scott P. West , Cynthia Arndt
发明人： Gregory T. Whiteker , Kim E. Arndt , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary A. Roth , Scott P. West , Cynthia Arndt
IPC分类号： C07D213/79 , C07D213/803
CPC分类号： C07D213/803 , C07D213/79
摘要： 4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinates by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation and transition metal assisted coupling.
摘要翻译： 通过涉及氟交换，胺化，卤素交换，卤化和过渡金属辅助偶联的一系列步骤，方便地从4,5,6-三氯吡啶酸盐制备4-氨基-5-氟-3-卤代-6-（取代的）吡啶甲酸盐。
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公开(公告)号：US08609855B2
公开(公告)日：2013-12-17
申请号：US13356691
申请日：2012-01-24
申请人： Gregory T. Whiteker , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary A. Roth , Scott P. West , Cynthia Arndt
发明人： Gregory T. Whiteker , Kim E. Arndt , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary A. Roth , Scott P. West
IPC分类号： C07D213/73
CPC分类号： C07D213/803 , C07D213/79
摘要： 4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinates by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation and transition metal assisted coupling.
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3.发明申请PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES 审中-公开制备4-氨基-5-氟-3-羟基-6-（取代的）吡啶甲酸酯的方法公开(公告)号：US20140039196A1
公开(公告)日：2014-02-06
申请号：US14049664
申请日：2013-10-09
申请人： Gregory T. Whiteker , Kim E. Arndt , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary Roth , Scott P. West
发明人： Gregory T. Whiteker , Kim E. Arndt , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary Roth , Scott P. West
IPC分类号： C07D213/803
CPC分类号： C07D213/803 , C07D213/79
摘要： 4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinates by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation and transition metal assisted coupling.
摘要翻译： 通过涉及氟交换，胺化，卤素交换，卤化和过渡金属辅助偶联的一系列步骤，方便地从4,5,6-三氯吡啶酸盐制备4-氨基-5-氟-3-卤代-6-（取代的）吡啶甲酸盐。
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4.发明授权Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates 有权制备4-氨基-5-氟-3-卤代-6-（取代）吡啶甲酸盐的方法公开(公告)号：US08927731B2
公开(公告)日：2015-01-06
申请号：US14049664
申请日：2013-10-09
申请人： Gregory T. Whiteker , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary Roth , Scott P. West
发明人： Gregory T. Whiteker , Kim E. Arndt , James M. Renga , Yuanming Zhu , Christian T. Lowe , Thomas L. Siddall , David E. Podhorez , Gary Roth , Scott P. West
IPC分类号： C07D213/79 , C07D213/803
CPC分类号： C07D213/803 , C07D213/79
摘要： 4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinates by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation and transition metal assisted coupling.
摘要翻译： 通过涉及氟交换，胺化，卤素交换，卤化和过渡金属辅助偶联的一系列步骤，方便地从4,5,6-三氯吡啶酸盐制备4-氨基-5-氟-3-卤代-6-（取代的）吡啶甲酸盐。
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5.发明申请PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES 有权制备4-氨基-5-氟-3-羟基-6-（取代的）吡啶甲酸酯的方法公开(公告)号：US20120190859A1
公开(公告)日：2012-07-26
申请号：US13356686
申请日：2012-01-24
申请人： Yuanming Zhu , Gregory T. Whiteker , James M. Renga , Kim E. Arndt , Gary A. Roth , David E. Podhorez , Scott P. West , Cynthia Arndt
发明人： Yuanming Zhu , Gregory T. Whiteker , James M. Renga , Kim E. Arndt , Gary A. Roth , David E. Podhorez , Scott P. West , Cynthia Arndt
IPC分类号： C07D213/79 , C07D213/803 , C07D213/81 , C07D213/84
CPC分类号： C07D213/81 , C07D213/78 , C07D213/79 , C07D213/803
摘要： 4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation, nitrile hydrolysis, esterification, and transition metal assisted coupling.
摘要翻译： 通过一系列涉及氟交换，胺化，卤素交换，卤化，腈水解，酯化等步骤的方法，可以方便地从4,5,6-三氯吡啶腈制备4-氨基-5-氟-3-卤代-6-（取代的） 和过渡金属辅助耦合。
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6.发明授权Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates 有权制备4-氨基-5-氟-3-卤代-6-（取代）吡啶甲酸盐的方法公开(公告)号：US08754231B2
公开(公告)日：2014-06-17
申请号：US13356686
申请日：2012-01-24
申请人： Yuanming Zhu , Gregory T. Whiteker , James M. Renga , Gary A. Roth , David E. Podhorez , Scott P. West , Cynthia Arndt
发明人： Yuanming Zhu , Gregory T. Whiteker , James M. Renga , Kim E. Arndt , Gary A. Roth , David E. Podhorez , Scott P. West
IPC分类号： C07D213/81
CPC分类号： C07D213/81 , C07D213/78 , C07D213/79 , C07D213/803
摘要： 4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation, nitrile hydrolysis, esterification, and transition metal assisted coupling.
摘要翻译： 通过一系列涉及氟交换，胺化，卤素交换，卤化，腈水解，酯化等步骤的方法，可以方便地从4,5,6-三氯吡啶腈制备4-氨基-5-氟-3-卤代-6-（取代的） 和过渡金属辅助耦合。
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7.发明申请PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES 审中-公开制备4-氨基-3-氯氟-6-（取代的）吡啶甲酸酯的方法公开(公告)号：US20120190857A1
公开(公告)日：2012-07-26
申请号：US13356669
申请日：2012-01-24
申请人： Kim E. Arndt , James M. Renga , Yuanming Zhu , Gregory T. Whiteker , Christian T. Lowe , Cynthia Arndt
发明人： Kim E. Arndt , James M. Renga , Yuanming Zhu , Gregory T. Whiteker , Christian T. Lowe , Cynthia Arndt
IPC分类号： C07D213/79 , C07D213/84 , C07D213/81 , C07D213/803
CPC分类号： C07D213/84 , C07D213/79 , C07D213/803 , C07D213/81
摘要： 4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange and hydrolysis, esterification and transition metal assisted coupling.
摘要翻译： 通过一系列涉及氟交换，胺化，卤素交换和水解，酯化和转化的步骤，方便地从3,4,5,6-四氯吡啶腈制备4-氨基-3-氯-5-氟-6-（取代的）吡啶甲酸盐 金属辅助联轴器。
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8.发明授权Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates 有权制备4-氨基-3-氯-5-氟-6-（取代）吡啶甲酸盐的方法公开(公告)号：US09067890B2
公开(公告)日：2015-06-30
申请号：US14171791
申请日：2014-02-04
IPC分类号： C07D213/803 , C07D213/79 , C07D213/81 , C07D213/84
CPC分类号： C07D213/84 , C07D213/79 , C07D213/803 , C07D213/81
摘要： 4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange and hydrolysis, esterification and transition metal assisted coupling.
摘要翻译： 通过一系列涉及氟交换，胺化，卤素交换和水解，酯化和转化的步骤，方便地从3,4,5,6-四氯吡啶腈制备4-氨基-3-氯-5-氟-6-（取代的）吡啶甲酸盐 金属辅助联轴器。
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9.发明申请PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES 审中-公开制备4-氨基-3-氯氟-6-（取代的）吡啶甲酸酯的方法公开(公告)号：US20140142317A1
公开(公告)日：2014-05-22
申请号：US14171791
申请日：2014-02-04
IPC分类号： C07D213/803 , C07D213/84
CPC分类号： C07D213/84 , C07D213/79 , C07D213/803 , C07D213/81
摘要： 4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange and hydrolysis, esterification and transition metal assisted coupling.
摘要翻译： 通过一系列涉及氟交换，胺化，卤素交换和水解，酯化和转化的步骤，方便地从3,4,5,6-四氯吡啶腈制备4-氨基-3-氯-5-氟-6-（取代的）吡啶甲酸盐 金属辅助联轴器。
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10.发明授权Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates 有权制备4-氨基-3-氯-5-氟-6-（取代）吡啶甲酸盐的方法公开(公告)号：US08609853B2
公开(公告)日：2013-12-17
申请号：US13356675
申请日：2012-01-24
IPC分类号： C07D213/84
CPC分类号： C07D213/807 , C07D213/79 , C07D213/803 , C07D213/84
摘要： 4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, reaction with hydrazine, halogenation, hydrolysis and esterification, and transition metal assisted coupling.
摘要翻译： 通过一系列涉及氟交换，胺化，与肼反应，卤化反应，水解和水解的步骤，可以方便地从3,4,5,6-四氯吡啶腈制备4-氨基-3-氯-5-氟-6-（取代的）吡啶甲酸盐 酯化和过渡金属辅助偶联。
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