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17 条记录 (耗时 0.019 秒)

    Triarylborane derivatives, their preparation and their use as synthesis intermediates
    6.
    发明授权
    Triarylborane derivatives, their preparation and their use as synthesis intermediates 失效
    三芳基硼烷衍生物，其制备及其作为合成中间体的用途

    公开(公告)号：US5374735A

    公开(公告)日：1994-12-20

    申请号：US166026

    申请日：1993-12-14

    申请人： Isaac Chekroun ,  Guy Rossey ,  Michel Magnat

    发明人： Isaac Chekroun ,  Guy Rossey ,  Michel Magnat

    IPC分类号： C07F5/02 ,  C07F7/10 ,  C07D257/04

    CPC分类号： C07F5/027

    摘要： Triarylborane derivatives corresponding to the formula (1) ##STR1## in which R either represents a group --CR.sub.1 R.sub.2 R.sub.3 where R.sub.1, R.sub.2 and R.sub.3 are each, independently of one another, a (C.sub.1 -C.sub.2)alkyl or aryl group, or represents a group --CH.sub.2 OR.sub.4 where R.sub.4 is a (C.sub.1 -C.sub.2)alkyl or benzyl group, or represents a group --Si(R.sub.5).sub.3 where R.sub.5 is a (C.sub.1 -C.sub.2)alkyl or aryl group, R being in the 1 or 2 position of the tetrazole ring, their preparation and their use as synthesis intermediates.

    摘要翻译： 对应于式（1）的三芳基硼烷衍生物其中R代表基团-CR1R2R3，其中R1，R2和R3彼此独立地为（C1-C2）烷基或芳基，或 表示基团-CH 2 OR 4，其中R 4是（C 1 -C 2）烷基或苄基，或代表基团-Si（R 5）3，其中R 5是（C 1 -C 2）烷基或芳基，R 1或2 四唑环的位置，它们的制备及其作为合成中间体的用途。

    2-(tetrazol-5-yl)-1,1'-biphenyl derivatives, their preparation and their use as synthetic intermediates
    8.
    发明授权
    2-(tetrazol-5-yl)-1,1'-biphenyl derivatives, their preparation and their use as synthetic intermediates 失效
    2-（四唑-5-基）-1,1'-联苯衍生物，其制备及其作为合成中间体的用途

    公开(公告)号：US5371233A

    公开(公告)日：1994-12-06

    申请号：US998055

    申请日：1992-12-29

    申请人： Marc Daumas ,  Christian Hoornaert ,  Isaac Chekroun ,  Manuel Bedoya-Zurita ,  Jose Ruiz-Montes ,  Guy Rossey ,  Helene Greciet

    发明人： Marc Daumas ,  Christian Hoornaert ,  Isaac Chekroun ,  Manuel Bedoya-Zurita ,  Jose Ruiz-Montes ,  Guy Rossey ,  Helene Greciet

    IPC分类号： C07D257/04 ,  C07D403/10

    CPC分类号： C07D257/04

    摘要： Compounds corresponding to the formula (I) ##STR1## in which X represents dibromomethyl, formyl, (C.sub.1-4)alkyl, or a group CH(OR.sub.5).sub.2 or CH(OH)OR.sub.5, wherein the or each R.sub.5 is hydrogen (C.sub.1-3)alkyl or the two R.sub.5 's in the case of CH(OR.sub.5).sub.2 are linked to provide a 1,3-dioxolane or 1,3-dioxane ring, and Y represents hydrogen, 1,1-dimethylethyl, triphenylmethyl, trimethylstannyl, tributylstannyl, (1,1-dimethylethyl)dimethylsilyl, (1,1-dimethylethyl)diphenylsilyl, 2-cyanoethyl, or a group CH.sub.2 OR.sub.6 wherein R.sub.6 is methyl, phenylmethyl, 1,1-dimethylethyl, 2,2,2-trichloroethyl, benzyloxycarbonyl or 2,2,2-trichloroethyloxycarbonyl, Y being in position 1 or 2 on the tetrazole ring. The compounds of formula (I) are useful as intermediates in the synthesis of compounds possessing therapeutic activity.

    摘要翻译： 对应于式（I）的化合物其中X表示二溴甲基，甲酰基，（C 1-4）烷基或CH（OR 5）2或CH（OH）OR 5基团，其中每个R 5为 氢（C 1-3）烷基或在CH（OR 5）2的情况下的两个R 5连接，得到1,3-二氧戊环或1,3-二恶烷环，Y代表氢，1,1-二甲基乙基，三苯基甲基 ，三甲基甲锡烷基，三丁基甲锡烷基，（1,1-二甲基乙基）二甲基甲硅烷基，（1,1-二甲基乙基）二苯基甲硅烷基，2-氰乙基或CH 2 OR 6，其中R 6是甲基，苯甲基，1,1-二甲基乙基， 三氯乙基，苄氧基羰基或2,2,2-三氯乙氧基羰基，Y在四唑环上位于1或2位。 式（I）的化合物可用作合成具有治疗活性的化合物的中间体。