公开(公告)号：US20210323938A1

公开(公告)日：2021-10-21

申请号：US17234660

申请日：2021-04-19

Applicant: H. LUNDBECK A/S

Inventor： Cheryl A. GRICE ,  Kurt G. GRIMM ,  Todd K. JONES ,  Giuseppe GUERCIO

IPC: C07D295/02

Abstract: Described herein is the manufacture of MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate including salts thereof.

公开(公告)号：US20240158360A1

公开(公告)日：2024-05-16

申请号：US18325798

申请日：2023-05-30

Applicant: H. Lundbeck A/S

Inventor： Cheryl A. GRICE ,  Kurt G. GRIMM ,  Todd K. JONES ,  Giuseppe GUERCIO

IPC: C07D295/02 ,  C07D295/023

CPC classification number: C07D295/02 ,  C07D295/023 ,  C07B2200/13

Abstract: Described herein is the manufacture of MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate including salts thereof.