公开(公告)号：US11542323B2

公开(公告)日：2023-01-03

申请号：US17088307

申请日：2020-11-03

Applicant: H. Lundbeck A/S

Inventor： Pekka Kallunki ,  Karina Fog ,  Louise Buur Vesterager ,  Ann-Louise Bergstrôm ,  Florence Sotty ,  David Satijn ,  Edward Van Den Brink ,  Paul Parren ,  Rik Rademaker ,  Tom Vink ,  Ibrahim John Malik ,  Liliana Christina Pereira Montezinho ,  Jeffrey B Stavenhagen

IPC: C07K16/18 ,  A61K51/00 ,  A61K39/395 ,  A61P25/16 ,  A61P25/28 ,  G01N33/68 ,  A61K39/00

Abstract: The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.