公开(公告)号：US12115208B2

公开(公告)日：2024-10-15

申请号：US16158928

申请日：2018-10-12

申请人： HIGH POINT UNIVERSITY

发明人： Meghan Scobee Blackledge ,  Patrick Andrew Vigueira ,  Heather B. Miller

IPC分类号： A61K38/14 ,  A61K31/335 ,  A61K31/553 ,  A61P31/04

CPC分类号： A61K38/14 ,  A61K31/335 ,  A61K31/553 ,  A61P31/04

摘要： Methods for treating a bacterial infection and for suppressing antibiotic resistance in a patient are described herein. Certain such methods generally involve administering an antibiotic and an adjuvant compound to a patient with a bacterial infection caused by Staphylococcus aureus, wherein the adjuvant compound comprises a fused tricyclic ring system with at least one halogen substituent. Compositions and kits containing such components are also described.

公开(公告)号：US20190125825A1

公开(公告)日：2019-05-02

申请号：US16158928

申请日：2018-10-12

申请人： HIGH POINT UNIVERSITY

发明人： Meghan Scobee Blackledge ,  Patrick Andrew Vigueira ,  Heather B. Miller

IPC分类号： A61K38/14 ,  A61K31/335 ,  A61P31/04 ,  A61K31/553

摘要： Methods for treating a bacterial infection and for suppressing antibiotic resistance in a patient are described herein. Certain such methods generally involve administering an antibiotic and an adjuvant compound to a patient with a bacterial infection caused by Staphylococcus aureus, wherein the adjuvant compound comprises a fused tricyclic ring system with at least one halogen substituent. Compositions and kits containing such components are also described.