公开(公告)号：US3914236A

公开(公告)日：1975-10-21

申请号：US45471374

申请日：1974-03-25

Applicant: HOECHST AG

Inventor： LERCH ULRICH ,  GRANZER ERNOLD

IPC: A61K31/47 ,  A61K31/472 ,  A61P3/06 ,  A61P3/08 ,  A61P9/10 ,  C07D217/22 ,  C07D217/24 ,  C07D227/06 ,  C07D401/04 ,  C07D521/00

CPC classification number: C07D231/12 ,  C07D217/22 ,  C07D217/24 ,  C07D233/56 ,  C07D249/08

Abstract: 1-(1-Imidazolyl)-isoquinolines of the general formula I and their physiologically tolerated salts,

IN WHICH R1, R2 and R3 represent hydrogen, alkyl of 1 to 4 carbon atoms or phenyl, R1, R2 and R3 may be identical or different, R4 represents hydrogen, alkyl of 1 to 4 carbon atoms, phenyl or chlorine, and R5 represents hydrogen, alkyl of 1 to 6 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, phenyl or chlorine, a process for preparing them and pharmaceutical preparations containing them as active ingredient.

Abstract translation: 通式I的1-（1-咪唑基） - 异喹啉及其生理上耐受的盐，其中R 1，R 2和R 3表示氢，1至4个碳原子的烷基或苯基，R 1，R 2和R 3可以相同或不同 ，R4表示氢，1-4个碳原子的烷基，苯基或氯，R5表示氢，1-6个碳原子的烷基，5-8个碳原子的环烷基，苯基或氯，它们的制备方法和药物制剂 含有它们作为活性成分。