公开(公告)号：US11633281B2

公开(公告)日：2023-04-25

申请号：US16745246

申请日：2020-01-16

申请人： Half Moon Medical, Inc. ,  Medtronic, Inc.

发明人： Arie Pieter Kappetein ,  James I. Fann ,  Hanson S. Gifford, III ,  Matthew McLean ,  Gaurav Krishnamurthy ,  Neil Zimmerman

IPC分类号： A61F2/24 ,  A61B5/0215 ,  A61B5/029 ,  A61B5/00 ,  A61F2/90

摘要： Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and/or left ventricular pressure.

公开(公告)号：US20210085462A1

公开(公告)日：2021-03-25

申请号：US17027681

申请日：2020-09-21

申请人： Half Moon Medical, Inc.

发明人： Hanson S. Gifford, III ,  Ben F. Brian, III ,  Matthew McLean ,  Gaurav Krishnamurthy ,  Neil Zimmerman ,  James I. Fann ,  Katie Miyashiro

IPC分类号： A61F2/24

摘要： Cardiac valve repair devices with coaptation members and multiple clip mechanisms and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an optional fixation member configured to engage tissue within a left atrium proximate to a native mitral valve, a coaptation member depending from the fixation member, and a plurality of clip mechanisms extending from a downstream portion of the coaptation member. The coaptation member can be positioned between the native leaflets and at least partially fill a space between the native leaflets. A first clip mechanism can engage a first portion of one of the native leaflets, and a second clip mechanism can engage another portion of the same native leaflet or an opposing native leaflet.

公开(公告)号：US20220160508A1

公开(公告)日：2022-05-26

申请号：US17456150

申请日：2021-11-22

申请人： Half Moon Medical, Inc.

发明人： Katherine Miyashiro ,  Hanson S. Gifford, III ,  James I. Fann ,  Ben F. Brian, III ,  Gaurav Krishnamurthy ,  Jose Gonzalez ,  Paul Gunning ,  Matthew McLean ,  Neil Zimmerman ,  Robert O'Grady ,  Douglas S. Sutton ,  Jean-Pierre Dueri ,  Ryan Helmuth ,  Marine De Gouy

IPC分类号： A61F2/24

摘要： Cardiac valve repair devices and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, a coaptation member configured to be positioned between one or more native leaflets of the cardiac valve to at least partially fill a space between the native leaflets. The cardiac valve repair device can further include one or more fixation mechanisms for securing the coaptation member in position between the leaflets. A cardiac valve repair device configured in accordance with additional embodiments of the present technology can include an atrial member and a ventricular member configured to sandwich one or more the native leaflets therebetween.

公开(公告)号：US20230040083A1

公开(公告)日：2023-02-09

申请号：US17973419

申请日：2022-10-25

申请人： Half Moon Medical, Inc.

发明人： Hanson S. Gifford, III ,  Matthew McLean ,  Gaurav Krishnamurthy ,  Neil Zimmerman

IPC分类号： A61F2/24

摘要： Cardiac valve repair devices with annuloplasty features and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an atrial fixation member configured to engage tissue within a left atrium proximate to a native mitral valve and a spring mechanism coupled to an inferior edge portion of the atrial fixation member. The spring mechanism has an extended state with a first length corresponding to a dimension of the atrial fixation member in a deployed state and a relaxed state with a shorter length corresponding to a desired dimension of the native valve annulus. When implanted, the spring mechanism contracts the atrial fixation member such that the native mitral annulus anchored to the atrial fixation member reduces in a cross-sectional dimension.

公开(公告)号：US20200289265A1

公开(公告)日：2020-09-17

申请号：US16817464

申请日：2020-03-12

申请人： Half Moon Medical, Inc.

发明人： Hanson S. Gifford, III ,  Matt McLean ,  Gaurav Krishnamurthy ,  Neil Zimmerman

IPC分类号： A61F2/24

摘要： Cardiac valve repair devices with annuloplasty features and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an atrial fixation member configured to engage tissue within a left atrium proximate to a native mitral valve and a spring mechanism coupled to an inferior edge portion of the atrial fixation member. The spring mechanism has an extended state with a first length corresponding to a dimension of the atrial fixation member in a deployed state and a relaxed state with a shorter length corresponding to a desired dimension of the native valve annulus. When implanted, the spring mechanism contracts the atrial fixation member such that the native mitral annulus anchored to the atrial fixation member reduces in a cross-sectional dimension.

公开(公告)号：US20220079755A1

公开(公告)日：2022-03-17

申请号：US17024667

申请日：2020-09-17

申请人： Half Moon Medical, Inc.

发明人： Neil Zimmerman, III ,  Jeffrey Martin ,  Jean-Pierre Dueri ,  Erik Thai ,  Andrew Johnston ,  Douglas Sutton ,  Cassandra Orth ,  Robert O'Grady ,  Jose Gonzalez ,  Matthew McLean ,  Gaurav Krishnamurthy

IPC分类号： A61F2/24

摘要： Delivery systems for implanting cardiac valve repair devices are disclosed herein. In some embodiments, a delivery system includes a delivery catheter, a hub shaft extending through the delivery catheter, and a core shaft extending through the hub shaft. The delivery catheter is configured to hold a valve repair device in a compressed configuration. The hub shaft includes a hub configured to releasably engage a first portion of the valve repair device, and the core shaft includes a plug configured to releasably engage a second portion of the valve repair device. When the valve repair device is unsheathed from the delivery catheter, the hub shaft and the core shaft are independently movable to axially elongate/compress the valve repair device. When the valve repair device is properly positioned, the hub can be actuated to release the first portion of the valve repair device, and the plug can be actuated to release the second portion of the valve repair device.

公开(公告)号：US20220079753A1

公开(公告)日：2022-03-17

申请号：US17194113

申请日：2021-03-05

申请人： Half Moon Medical, Inc.

发明人： Neil Zimmerman ,  Jeffrey Martin ,  Jean-Pierre Dueri ,  Erik Thai ,  Andrew Johnston ,  Douglas Sutton ,  Cassandra Orth ,  Robert O'Grady ,  Jose Gonzalez ,  Matthew McLean ,  Gaurav Krishnamurthy

IPC分类号： A61F2/24 ,  A61F2/95

摘要： Delivery systems for implanting cardiac valve repair devices are disclosed herein. In some embodiments, a delivery system includes a delivery catheter, a hub shaft extending through the delivery catheter, and a core shaft extending through the hub shaft. The delivery catheter is configured to hold a valve repair device in a compressed configuration. The hub shaft includes a hub configured to releasably engage a first portion of the valve repair device, and the core shaft includes a plug configured to releasably engage a second portion of the valve repair device. When the valve repair device is unsheathed from the delivery catheter, the hub shaft and the core shaft are independently movable to axially elongate/compress the valve repair device. When the valve repair device is properly positioned, the hub can be actuated to release the first portion of the valve repair device, and the plug can be actuated to release the second portion of the valve repair device.

公开(公告)号：US20200275974A1

公开(公告)日：2020-09-03

申请号：US16650837

申请日：2018-09-14

申请人： Half Moon Medical, Inc.

发明人： Hanson S. Gifford, III ,  Matt McLean ,  Gaurav Krishnamurthy ,  James Fann ,  Doug Sutton

IPC分类号： A61B18/14 ,  A61B18/18

摘要： Devices and minimally invasive methods for reducing the size of a cardiac valve annulus in a beating heart. Embodiments of the methods can include advancing an energy delivery catheter into the heart proximate a cardiac valve annulus, the energy delivery catheter having at least two electrodes. Then advancing the two electrodes such that the two electrodes pierce into the cardiac valve annulus at a distance from one another. The methods further include applying an approximating force to at least one of the two electrodes, thereby reducing the distance between the two electrodes, and applying energy between the at least two electrodes, thereby heating and shrinking the annulus in a direction of the approximating force.

公开(公告)号：US20200222185A1

公开(公告)日：2020-07-16

申请号：US16745246

申请日：2020-01-16

申请人： Half Moon Medical, Inc.

发明人： Arie Pieter Kappetein ,  James I. Fann ,  Hanson S. Gifford, III ,  Matthew McLean ,  Gaurav Krishnamurthy ,  Neil Zimmerman

IPC分类号： A61F2/24 ,  A61F2/90 ,  A61B5/0215 ,  A61B5/00 ,  A61B5/029

摘要： Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and/or left ventricular pressure.

公开(公告)号：US11504237B2

公开(公告)日：2022-11-22

申请号：US16817464

申请日：2020-03-12

申请人： Half Moon Medical, Inc.

发明人： Hanson S. Gifford, III ,  Matthew McLean ,  Gaurav Krishnamurthy ,  Neil Zimmerman

IPC分类号： A61F2/24

摘要： Cardiac valve repair devices with annuloplasty features and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, an atrial fixation member configured to engage tissue within a left atrium proximate to a native mitral valve and a spring mechanism coupled to an inferior edge portion of the atrial fixation member. The spring mechanism has an extended state with a first length corresponding to a dimension of the atrial fixation member in a deployed state and a relaxed state with a shorter length corresponding to a desired dimension of the native valve annulus. When implanted, the spring mechanism contracts the atrial fixation member such that the native mitral annulus anchored to the atrial fixation member reduces in a cross-sectional dimension.