公开(公告)号：US20230233567A1

公开(公告)日：2023-07-27

申请号：US17999799

申请日：2021-05-17

Applicant: Hanmi Pharm. Co., Ltd. ,  Genentech, Inc.

Inventor： Tae Won KIM ,  Yoon-hee HONG ,  Young Su NOH ,  Matthew Tsn-Wei CHANG ,  Shiva MALEK ,  Yibing YAN ,  Ivana Yen Yen YEN

IPC: A61K31/519 ,  A61P35/00 ,  A61P17/00

CPC classification number: A61K31/519 ,  A61P35/00 ,  A61P17/00

Abstract: Provided are methods for the use of belvarafenib to treat cancer having at least one mutation selected from a BRAFV600E mutation, a KRASG12V mutation, a KRASG12D mutation, a KRASG12C mutation, a KRASG12R mutation, a KRASG13D mutation, a KRASQ61H mutation, a NRASG12D mutation, a NRASG13D mutation, a NRASQ61K mutation, a NRASQ61L mutation, a NRASQ61R mutation, and a NRASG12C mutation.