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公开(公告)号：US07252686B2
公开(公告)日：2007-08-07
申请号：US10639871
申请日：2003-08-13
IPC分类号： A61F2/44
CPC分类号： A61B17/3468 , A61B17/3472 , A61B17/8852 , A61B2017/00261
摘要： Devices, kits, and methods are provided for treating a bone structure, e.g., a vertebra, with a compression fracture. Wedges can be introduced into the bone structure in a direction that is lateral to the compression fracture, and stacked on tope of each to apply forces to the bone structure to reduce the compression fracture. The wedges can be introduced into the bone structure using a cannula. The wedges can be introduced as wedge pairs, in which case, a subsequent wedge pair can be introduced between a previously introduced wedge pair in order to drive the previously introduced wedges apart to create the stacking arrangement. Optionally, the wedges can be provided with longitudinal bores, in which case, they can be introduced into the bone structure, over a guide member that is threaded through the bores.
摘要翻译： 提供了用压缩骨折治疗骨骼结构例如椎骨的装置，试剂盒和方法。 楔子可以沿着压缩断裂侧面的方向被引入骨结构中，并且将其堆叠在每个的顶部以向骨结构施加力以减少压缩性骨折。 可以使用插管将楔形物引入骨结构。 楔形物可以作为楔形对引入，在这种情况下，可以在先前引入的楔形对之间引入随后的楔形对，以便将先前引入的楔形物分开以产生堆叠布置。 可选地，楔形物可以设置有纵向孔，在这种情况下，它们可以在穿过孔的引导构件上引入到骨结构中。
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2.发明授权Apparatus and methods for reducing compression bone fractures using high strength ribbed members 失效使用高强度肋骨构件减少压缩性骨折的装置和方法公开(公告)号：US07513900B2
公开(公告)日：2009-04-07
申请号：US10674723
申请日：2003-09-29
申请人： Harold F. Carrison , Lex P. Jansen
发明人： Harold F. Carrison , Lex P. Jansen
IPC分类号： A61B17/56
CPC分类号： A61B17/885 , A61B17/7097 , A61B17/8858
摘要： Devices and methods are provided for treating a bone structure (such as, e.g., reducing a bone fracture, e.g., a vertebral compression fracture, or stabilizing adjacent bone structure, e.g., vertebrae) is provided. The device comprises rigid or semi-rigid members, each of which comprises a common base and a plurality of ribs that extent along the a longitudinal portion of the common base. The device is configured to be placed in a collapsed state by engaging the pluralities of ribs of the members in an interposed arrangement, and configured to be placed in a deployed state by disengaging the pluralities of ribs. The ribs can be any shape, e.g., flutes, that allows opposing ribs to intermesh with one another. In this manner, the device has a relatively small profile when placed in the collapsed state, so that it can be introduced through small openings within the bone structure, while preserving the shear strength of the members during deployment of the device.
摘要翻译： 提供了用于治疗骨结构的装置和方法（例如，例如减少骨折，例如椎骨压缩性骨折，或稳定相邻的骨结构，例如椎骨）。 该装置包括刚性或半刚性构件，每个构件包括公共底座和沿公共底座的纵向部分延伸的多个肋。 该装置被构造成通过以插入的方式接合构件的多个肋而被置于折叠状态，并且构造成通过分离多个肋而被放置在展开状态。 肋可以是允许相对的肋相互啮合的任何形状，例如凹槽。 以这种方式，当设置在折叠状态时，该装置具有相对较小的轮廓，使得其可以通过骨结构内的小开口引入，同时在装置展开期间保持构件的剪切强度。
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公开(公告)号：US07591822B2
公开(公告)日：2009-09-22
申请号：US10786251
申请日：2004-02-24
IPC分类号： A61B17/56
CPC分类号： A61B17/7098 , A61B17/8811 , A61M25/0069 , A61M25/007 , A61M2210/02
摘要： Cannulas are provided for delivering therapeutic material to a treatment site. The cannula includes a cannula body with a plurality of openings at the distal end, including a longitudinal opening and a plurality of transverse openings that are axially spaced from each other. The cannula also includes a plunger that is configured to be slidably disposed within the cannula lumen. When the plunger is proximally displaced in the cannula lumen, the plunger seals the distal end and deflects the therapeutic material out the transverse openings. As the plunger is proximally displaced within the lumen, the therapeutic material is forced to perfuse out transverse openings located proximal of the plunger position. In one embodiment, the plunger includes an additional pliable sealable member. In another embodiment, the distal end of the cannula body may be implanted by separating the distal end from the cannula body.
摘要翻译： 提供插管用于将治疗材料递送至治疗部位。 套管包括在远端具有多个开口的套管主体，包括纵向开口和彼此轴向间隔开的多个横向开口。 插管还包括被构造成可滑动地设置在套管内腔内的柱塞。 当柱塞在套管腔中向近端移位时，柱塞密封远端并使治疗材料偏离横向开口。 当柱塞在腔内向近端移位时，治疗材料被迫灌注位于柱塞位置附近的横向开口。 在一个实施例中，柱塞包括附加的柔韧的可密封构件。 在另一个实施例中，套管本体的远端可以通过将远端与套管主体分离而被植入。
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公开(公告)号：US06730095B2
公开(公告)日：2004-05-04
申请号：US10183220
申请日：2002-06-26
IPC分类号： A61B1758
CPC分类号： A61B17/7098 , A61B17/8811 , A61M25/0069 , A61M25/007 , A61M2210/02
摘要： Cannulas are provided for delivering therapeutic material to a treatment site. The cannula includes a cannula body with a plurality of openings at the distal end, including a longitudinal opening and a plurality of transverse openings that are axially spaced from each other. The cannula also includes a plunger that is configured to be slidably disposed within the cannula lumen. When the plunger is proximally displaced in the cannula lumen, the plunger seals the distal end and deflects the therapeutic material out the transverse openings. As the plunger is proximally displaced within the lumen, the therapeutic material is forced to perfuse out transverse openings located proximal of the plunger position. In one embodiment, the plunger includes an additional pliable sealable member. In another embodiment, the distal end of the cannula body may be implanted by separating the distal end from the cannula body.
摘要翻译： 提供插管用于将治疗材料递送至治疗部位。 套管包括在远端具有多个开口的套管主体，包括纵向开口和彼此轴向间隔开的多个横向开口。 插管还包括被构造成可滑动地设置在套管内腔内的柱塞。 当柱塞在套管腔中向近端移位时，柱塞密封远端并使治疗材料偏离横向开口。 当柱塞在腔内向近端移位时，治疗材料被迫灌注位于柱塞位置附近的横向开口。 在一个实施例中，柱塞包括附加的柔韧的可密封构件。 在另一个实施例中，套管本体的远端可以通过将远端与套管主体分离而被植入。
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公开(公告)号：US07901407B2
公开(公告)日：2011-03-08
申请号：US10211492
申请日：2002-08-02
IPC分类号： A61F2/46
CPC分类号： A61B17/1617 , A61B17/1671 , A61B17/1757 , A61B17/885 , A61B2017/8838 , A61F2002/4602
摘要： Apparatus for delivering a media to an anatomic void within a bone structure and compacting the media within the anatomic void includes a delivery device and a compaction device. The delivery device includes a tubular element, a guidewire, and a removal element. The removal element is capable of forming a void at a target site within the bone structure by cutting and/or deforming target bone tissue. A distal end of the guidewire may be detachable as a safety feature. The compaction device includes an elongate member and a vibration device connected to the proximal end of the elongate member. The vibration device creates vibration at the distal end of the elongate member, so that the media is mixed and/or compacted within the anatomic void.
摘要翻译： 用于将介质输送到骨结构内的解剖空隙并压实解剖空隙内的介质的装置包括输送装置和压实装置。 输送装置包括管状元件，导丝和去除元件。 移除元件能够通过切割和/或变形靶骨组织而在骨结构内的目标部位形成空隙。 导线的远端可以作为安全特征而可拆卸。 压实装置包括细长构件和连接到细长构件的近端的振动装置。 振动装置在细长构件的远端处产生振动，使得介质在解剖空隙内混合和/或压实。
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公开(公告)号：US06830561B2
公开(公告)日：2004-12-14
申请号：US10142575
申请日：2002-05-08
IPC分类号： A61M532
CPC分类号： A61M25/0113 , A61M25/0119 , A61M25/0662 , A61M2025/0007 , A61M2025/0681
摘要： A device for accessing the spinal canal of a patient includes an introducer and a protective sleeve that is attached at one end thereof to a proximal end of the introducer. The protective sleeve has an outer stationary portion and an inner moveable portion. The outer and inner portions of the protective sleeve are separated by a crown region. A catheter is disposed inside the protective sleeve. During operation, the protective sleeve is advanced within the spinal canal to form a protective barrier between the catheter and the spinal cord. The catheter is advanced and retracted within the protective sleeve.
摘要翻译： 用于接近患者的椎管的装置包括导引器和保护套筒，其在其一端附接到导引器的近端。 保护套具有外固定部和内可动部。 保护套的外部和内部由冠部区域分开。 导管设置在保护套内。 在操作期间，保护套在椎管内前进，以在导管和脊髓之间形成保护屏障。 导管先进并在保护套内缩回。
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7.发明授权公开(公告)号：US06960215B2
公开(公告)日：2005-11-01
申请号：US10142133
申请日：2002-05-08
CPC分类号： A61B17/7097 , A61B17/12027 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12172 , A61B17/7098 , A61B2017/1205 , A61B2017/12063 , A61B2017/22051
摘要： Devices and methods for the controlled delivery of therapeutic agents into bone and soft tissue to prevent the unintentional migration of therapeutic agents from the treatment site. The containment device can be made of a fabric or membrane that is porous, semi-porous, non-porous, bio-resorbable, or non-resorbable materials. A containment device is advanced to the interior of the target structure and filled with a therapeutic agent. The containment device may be permanently or temporarily implanted. Where permanent implantation is desired, the containment device may be detached via a severable junction.
摘要翻译： 用于将治疗剂控制递送到骨和软组织中以防止治疗剂从治疗部位意外迁移的装置和方法。 容纳装置可以由多孔，半多孔，无孔，生物可吸收或不可再吸收材料的织物或膜制成。 容纳装置前进到目标结构的内部并填充有治疗剂。 容纳装置可以永久地或临时植入。 在需要永久性植入的情况下，容纳装置可以通过可分离的连接部分离。
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公开(公告)号：US08317772B2
公开(公告)日：2012-11-27
申请号：US13045102
申请日：2011-03-10
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
摘要翻译： 导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。 细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。 近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。 第一和第二加强件同轴地缠绕在近端内衬的外部。 远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。 第一加强件在到达远端部分之前终止。
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公开(公告)号：US20110288553A1
公开(公告)日：2011-11-24
申请号：US12953278
申请日：2010-11-23
申请人： Lex P. Jansen , John W. Davis , John T. To , Singfatt Chin , Myra I. L. Fabro
发明人： Lex P. Jansen , John W. Davis , John T. To , Singfatt Chin , Myra I. L. Fabro
IPC分类号： A61B17/16
CPC分类号： A61B17/1671 , A61B17/1615 , A61B17/1617 , A61B17/162 , A61B17/1622 , A61B17/1628 , A61B17/1633 , A61B17/1637 , A61B17/1644 , A61B17/1697
摘要： Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. Some of the bone removal devices include expandable members which may be used to control the forced exerted and/or position of the bone removal mechanism, and to protect neurovascular structures and other soft tissue structures from the bone removal mechanism. Other bone removal devices include a trephine with a viewing window and a guide wire lumen used to position the trephine at a target tissue site using an anchored wire. The viewing window may be used to monitor structures or tissues adjacent to the target tissue site.
摘要翻译： 用于治疗脊柱狭窄的系统和方法包括用于进行椎间孔切开术或其他骨移除手术的内窥镜检查装置和骨移除装置。 骨去除装置中的一些包括可用于控制骨移除机构的强制施加和/或位置的可扩张构件，以及保护神经血管结构和其他软组织结构免受骨移除机构的影响。 其他骨去除装置包括具有观察窗的环钻和用于使用锚定线将环管定位在目标组织部位的导丝腔。 观察窗可用于监测与目标组织部位相邻的结构或组织。
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10.发明申请公开(公告)号：US20080051819A1
公开(公告)日：2008-02-28
申请号：US11730347
申请日：2007-03-30
申请人： Nishith Chasmawala , Bryan J. Auyoung , Gorman Gong , Alex Hsia , Lex P. Jansen , Christopher U. Phan
发明人： Nishith Chasmawala , Bryan J. Auyoung , Gorman Gong , Alex Hsia , Lex P. Jansen , Christopher U. Phan
IPC分类号： A61M29/00
CPC分类号： A61B17/8855 , A61B2017/00557 , A61B2017/00867 , A61M25/01 , A61M25/1006 , A61M25/1034 , A61M25/1038 , A61M25/104 , A61M2025/0063 , A61M2025/1004 , A61M2025/1031 , A61M2025/1088
摘要： In some embodiments, an apparatus includes an elongated member, an expandable member coupled to the elongated member, and an outer sheath. The outer sheath, which can be constructed from a different material than the expandable member, is disposed about the expandable member such that an outer surface of the expandable member is in discontinuous contact with an inner surface of the outer sheath. The expandable member and the outer sheath are configured to cooperatively displace a bone structure when moving between a collapsed configuration and an expanded configuration.
摘要翻译： 在一些实施例中，装置包括细长构件，联接到细长构件的可扩张构件和外护套。 可以由不同于可膨胀构件的材料构成的外护套围绕可膨胀构件设置，使得可膨胀构件的外表面与外护套的内表面不连续地接触。 可扩张构件和外护套构造成当在折叠构型和扩张构型之间移动时协同地移位骨结构。
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