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公开(公告)号：US11078499B2
公开(公告)日：2021-08-03
申请号：US16286411
申请日：2019-02-26
摘要： The present invention provides for a genetically modified host cell comprising a first polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase, and having an enzymatic activity to decarboxylate a phenylacetic acid into a toluene and a carbon dioxide, and a second polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase activating enzyme, and having an enzymatic activity to cleave a S-adenosylmethionine (SAM) to form a methionine and a 5′-deoxyadenosyl radical.
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公开(公告)号：US10913935B2
公开(公告)日：2021-02-09
申请号：US14216929
申请日：2014-03-17
申请人： Harry R. Beller
发明人： Harry R. Beller
IPC分类号： C12N9/02 , C12P7/64 , C12P7/26 , C02F3/34 , C12N1/32 , C02F3/28 , C12N9/16 , C02F101/16 , C02F101/10 , C02F103/36 , C02F101/32
摘要： The present invention provides for a genetically modified host cell or bacterium capable of producing an organic molecule, wherein the bacterium is capable of using hydrogen sulfide as an electron donor, carbon dioxide (CO2) as a carbon source, and/or nitrate as an electron acceptor. The present invention is useful in the wastewater treatment industry, in particular in municipal wastewater treatment plants (WWTP).
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公开(公告)号：US20200270642A1
公开(公告)日：2020-08-27
申请号：US16286411
申请日：2019-02-26
摘要： The present invention provides for a genetically modified host cell comprising a first polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase, and having an enzymatic activity to decarboxylate a phenylacetic acid into a toluene and a carbon dioxide, and a second polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase activating enzyme, and having an enzymatic activity to cleave a S-adenosylmethionine (SAM) to form a methionine and a 5′-deoxyadenosyl radical.
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公开(公告)号：US20210002671A9
公开(公告)日：2021-01-07
申请号：US16286411
申请日：2019-02-26
摘要： The present invention provides for a genetically modified host cell comprising a first polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase, and having an enzymatic activity to decarboxylate a phenylacetic acid into a toluene and a carbon dioxide, and a second polypeptide comprising a sequence having at least 70% amino acid sequence identity with a phenylacetate decarboxylase activating enzyme, and having an enzymatic activity to cleave a S-adenosylmethionine (SAM) to form a methionine and a 5′-deoxyadenosyl radical.
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公开(公告)号：US20150184133A1
公开(公告)日：2015-07-02
申请号：US14216929
申请日：2014-03-17
申请人： Harry R. Beller
发明人： Harry R. Beller
CPC分类号： C12N9/001 , C02F3/28 , C02F3/342 , C02F3/345 , C02F2101/101 , C02F2101/163 , C02F2101/32 , C02F2103/36 , C02F2303/08 , C12N1/32 , C12N9/16 , C12P7/26 , C12P7/6409 , C12Y103/03006
摘要： The present invention provides for a genetically modified host cell or bacterium capable of producing an organic molecule, wherein the bacterium is capable of using hydrogen sulfide as an electron donor, carbon dioxide (CO2) as a carbon source, and/or nitrate as an electron acceptor. The present invention is useful in the wastewater treatment industry, in particular in municipal wastewater treatment plants (WWTP).
摘要翻译： 本发明提供能够产生有机分子的经遗传修饰的宿主细胞或细菌，其中细菌能够使用硫化氢作为电子给体，二氧化碳（CO 2）作为碳源，和/或硝酸盐作为电子 受体。 本发明在污水处理工业中尤其适用于城市污水处理厂（WWTP）。
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