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公开(公告)号:US20090209606A1
公开(公告)日:2009-08-20
申请号:US12372910
申请日:2009-02-18
申请人: Heather Helene Bendall , Gary T. Elliott , Lorenzo M. Leoni , Christina Carol Niemeyer , Pratik S. Multani
发明人: Heather Helene Bendall , Gary T. Elliott , Lorenzo M. Leoni , Christina Carol Niemeyer , Pratik S. Multani
IPC分类号: A61K31/4184 , A61P35/00
CPC分类号: A61K31/4184
摘要: Methods and compositions for treating cancers characterized by death-resistant cancer cells are described. In general, such methods involve administration of a therapeutically effective amount of a compound that induces mitotic catastrophe in the some, and preferably most or all, of the cancerous cells. Methods for assessing the efficacy of such treatments are also provided.
摘要翻译: 描述了以死亡抗性癌细胞为特征的治疗癌症的方法和组合物。 通常,这些方法包括给予治疗有效量的在一些,优选大多数或全部癌细胞中诱导有丝分裂突变的化合物。 还提供了评估这种治疗效果的方法。