专利检索 ap:("Hebei University of Science & Technology") AND inv:"Huajie ZHU" 第 1 页

1.

发明公开
NITROGEN-CONTAINING POLYCYCLIC AROMATIC COMPOUND, and PREPARATION METHOD AND APPLICATION THEREOF 审中-公开

公开(公告)号：US20240140950A1

公开(公告)日：2024-05-02

申请号：US18398201

申请日：2023-12-28

申请人： Hebei University of Science & Technology

发明人： Huajie ZHU

IPC分类号： C07D471/22 , A61P35/00

CPC分类号： C07D471/22 , A61P35/00

摘要： The present application provides a nitrogen-containing polycyclic aromatic compound and its preparation method and application. The nitrogen-containing polycyclic aromatic compound has a structure of Formula I, has an excellent broad-spectrum anti-tumor activity, and shows an inhibitory activity comparable to cisplatin on cervical cancer cells, breast cancer cells, melanoma cells, lung cancer cells and myeloma cells. Compared with cisplatin, the compound also has lower toxicity, and may be used as a lead compound for the development of new anti-tumor drugs.