公开(公告)号：US6124470A

公开(公告)日：2000-09-26

申请号：US733392

申请日：1996-10-18

申请人： Heinrich Angenendt ,  Bert Willi Portz ,  Horst Walter

发明人： Heinrich Angenendt ,  Bert Willi Portz ,  Horst Walter

IPC分类号： B01D19/04 ,  B01F17/02 ,  C07D235/26

CPC分类号： C07D235/26 ,  B01D19/0404

摘要： The present invention relates to a process for working up reaction mixtures containing benzimidazolones of the formula (I) ##STR1## prepared by reacting o-phenylenediamines and urea in a water-insoluble solvent, where in formula (I) R.sup.1, R.sup.2 and R.sup.3 are identical or different and independently of one another are a hydrogen atom, an alkyl, alkoxy or alkylsulfonyl group having in each case 1 to 6 carbon atoms, chlorine, bromine, a substituted or unsubstituted phenyl group, a carboxylic acid, methylcarbonyl, phenylcarbonyl, methoxycarbonyl, carbamoyl, methylcarbamoyl or phenylcarbamoyl group, a hydroxyl group, cyano group or nitro group, by adding a wetting agent and a defoamer to the reaction mixture, distilling off the solvent azeotropically with the addition of water and with stirring and filtering off the benzimidazolone from the aqueous suspension arising.

摘要翻译： 本发明涉及一种用于处理含有式（I）的苯并咪唑酮的反应混合物的方法，该方法通过在邻苯二胺和尿素在不溶于水的溶剂中反应而制备，其中式（I）R1，R2和R3相同或不同 并且彼此独立地是氢原子，烷基，烷氧基或烷基磺酰基，其各自为1至6个碳原子，氯，溴，取代或未取代的苯基，羧酸，甲基羰基，苯基羰基，甲氧基羰基，氨基甲酰基， 甲基氨基甲酰基或苯基氨基甲酰基，羟基，氰基或硝基，通过向反应混合物中加入润湿剂和消泡剂，在加入水的同时共沸蒸馏除去溶剂，并从水悬浮液中搅拌和过滤掉苯并咪唑酮 产生。