公开(公告)号：US20240254101A1

公开(公告)日：2024-08-01

申请号：US17909792

申请日：2021-03-15

申请人： HEPTARES THERAPEUTICS LIMITED

发明人： Sarah Joanne BUCKNELL ,  Stephen Paul WATSON ,  Michael Alistair O'BRIEN

IPC分类号： C07D401/04 ,  A61K31/4439 ,  C07D401/14 ,  C07D405/14

CPC分类号： C07D401/04 ,  A61K31/4439 ,  C07D401/14 ,  C07D405/14

摘要： The disclosures herein relate to novel compounds of Formula (1); and salts thereof, wherein X, Y, R1, R2, R3 and R4 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with GPR52 receptors.

公开(公告)号：US20230348416A1

公开(公告)日：2023-11-02

申请号：US18023411

申请日：2021-08-31

申请人： Heptares Therapeutics Limited

发明人： Sarah Joanne BUCKNELL ,  Stephen Paul WATSON ,  Michael Alistair O'BRIEN

IPC分类号： C07D401/04 ,  C07D405/14 ,  C07D491/04

CPC分类号： C07D401/04 ,  C07D405/14 ,  C07D491/04

摘要： The disclosures herein relate to novel compounds of Formula (1): or a salt thereof, wherein Q, V, L, W, R1 and R2 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of disorders associated with GPR52 receptors.