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1.发明申请THERAPEUTIC AGENT FOR A LOWER URINARY TRACT DISEASE AND AN AGENT FOR IMPROVING A LOWER URINARY TRACT SYMPTOM 有权用于下尿路疾病的治疗药物和用于改善下尿路症状的药剂公开(公告)号：US20110150858A1
公开(公告)日：2011-06-23
申请号：US12996495
申请日：2009-07-01
申请人： Hirobumi Senga , Yongling Wan , Masato Honma
发明人： Hirobumi Senga , Yongling Wan , Masato Honma
CPC分类号： A61K38/4833
摘要： The present invention provides a therapeutic agent for a lower urinary tract disease such as cystitis, interstitial cystitis, prostatitis, benign prostatic hyperplasia etc., which are considered as refractory disease, and an agent for improving a lower urinary tract symptom associated with the lower urinary tract disease.
摘要翻译： 本发明提供了被认为是难治性疾病的下尿路疾病如膀胱炎，间质性膀胱炎，前列腺炎，良性前列腺增生等的治疗剂，以及用于改善与下尿路相关的下尿路症状的药剂 道疾病
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2.发明授权公开(公告)号：US08795655B2
公开(公告)日：2014-08-05
申请号：US12996495
申请日：2009-07-01
申请人： Hirobumi Senga , Yongling Wan , Masato Honma
发明人： Hirobumi Senga , Yongling Wan , Masato Honma
IPC分类号： A61K38/48
CPC分类号： A61K38/4833
摘要： The present invention provides a therapeutic agent for a lower urinary tract disease such as cystitis, interstitial cystitis, prostatitis, benign prostatic hyperplasia etc., which are considered as refractory disease, and an agent for improving a lower urinary tract symptom associated with the lower urinary tract disease.
摘要翻译： 本发明提供了被认为是难治性疾病的下尿路疾病如膀胱炎，间质性膀胱炎，前列腺炎，良性前列腺增生等的治疗剂，以及用于改善与下尿路相关的下尿路症状的药剂 道疾病
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公开(公告)号：US20060088519A1
公开(公告)日：2006-04-27
申请号：US11314443
申请日：2005-12-21
申请人： Hirobumi Senga , Caixia Li , Yongling Wan , Lishui Chang
发明人： Hirobumi Senga , Caixia Li , Yongling Wan , Lishui Chang
IPC分类号： A61K38/48
CPC分类号： A61K38/363
摘要： A malignant tumor-inhibiting preparation is provided which comprises Des A fibrin and therefore can inhibit the spreading and migration of malignant tumor cells and thereby can inhibit the malignant tumors.
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公开(公告)号：US08481047B2
公开(公告)日：2013-07-09
申请号：US11818783
申请日：2007-06-15
申请人： Hirobumi Senga , Caixia Li , Yongling Wan , Lishui Chang
发明人： Hirobumi Senga , Caixia Li , Yongling Wan , Lishui Chang
IPC分类号： A61K39/385
CPC分类号： A61K38/363
摘要： A malignant tumor-inhibiting preparation is provided which comprises Des A fibrin and therefore can inhibit the spreading and migration of malignant tumor cells and thereby can inhibit the malignant tumors.
摘要翻译： 提供了一种恶性肿瘤抑制制剂，其包含Des A纤维蛋白，因此可以抑制恶性肿瘤细胞的扩散和迁移，从而可以抑制恶性肿瘤。
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公开(公告)号：US20090018062A1
公开(公告)日：2009-01-15
申请号：US11818783
申请日：2007-06-15
申请人： Hirobumi Senga , Caixia Li , Yongling Wan , Lishui Chang
发明人： Hirobumi Senga , Caixia Li , Yongling Wan , Lishui Chang
CPC分类号： A61K38/363
摘要： A malignant tumor-inhibiting preparation is provided which comprises Des A fibrin and therefore can inhibit the spreading and migration of malignant tumor cells and thereby can inhibit the malignant tumors.
摘要翻译： 提供了一种恶性肿瘤抑制制剂，其包含Des A纤维蛋白，因此可以抑制恶性肿瘤细胞的扩散和迁移，从而可以抑制恶性肿瘤。
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公开(公告)号：US20100247510A1
公开(公告)日：2010-09-30
申请号：US12743162
申请日：2008-12-12
申请人： Hirobumi Senga , Yongling Wan
发明人： Hirobumi Senga , Yongling Wan
CPC分类号： A61K31/675 , A61K31/704 , A61K38/4833 , A61K45/06 , A61K2300/00
摘要： The present invention provides an agent for reducing a side effect of an anticancer drug, which comprises a thrombin-like enzyme.
摘要翻译： 本发明提供了减少抗凝药物的副作用的试剂，其包含凝血酶样酶。
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7.发明申请Preparation comprising batroxobin for inhibiting local invasion of malignant tumors 有权包括巴曲酶用于抑制恶性肿瘤局部浸润的制剂公开(公告)号：US20070104706A1
公开(公告)日：2007-05-10
申请号：US11638069
申请日：2006-12-13
申请人： Hirobumi Senga , Yongling Wan , Lishui Chang
发明人： Hirobumi Senga , Yongling Wan , Lishui Chang
IPC分类号： A61K38/48
CPC分类号： A61K38/482
摘要： A preparation for inhibiting local invasion of malignant tumors is provided which comprises batroxobin and therefore can inhibit local invasion of malignant tumors. A preparation for encapsulating malignant tumor tissues is also provided which comprises batroxobin and therefore can cause or promote formation of capsule-like tissue around malignant tumor tissues.
摘要翻译： 提供了抑制恶性肿瘤局部浸润的制剂，其包括巴曲酶，因此可以抑制恶性肿瘤的局部侵袭。 还提供了包封恶性肿瘤组织的制剂，其包括巴曲酶，因此可以引起或促进恶性肿瘤组织周围的胶囊样组织的形成。
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8.发明授权Preparation comprising batroxobin for inhibiting local invasion of malignant tumors 有权包括巴曲酶用于抑制恶性肿瘤局部浸润的制剂公开(公告)号：US07691371B2
公开(公告)日：2010-04-06
申请号：US11638069
申请日：2006-12-13
申请人： Hirobumi Senga , Yongling Wan , Lishui Chang
发明人： Hirobumi Senga , Yongling Wan , Lishui Chang
CPC分类号： A61K38/482
摘要： A preparation for inhibiting local invasion of malignant tumors is provided which comprises batroxobin and therefore can inhibit local invasion of malignant tumors. A preparation for encapsulating malignant tumor tissues is also provided which comprises batroxobin and therefore can cause or promote formation of capsule-like tissue around malignant tumor tissues.
摘要翻译： 提供了抑制恶性肿瘤局部浸润的制剂，其包括巴曲酶，因此可以抑制恶性肿瘤的局部侵袭。 还提供了包封恶性肿瘤组织的制剂，其包括巴曲酶，因此可以引起或促进恶性肿瘤组织周围的胶囊样组织的形成。
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公开(公告)号：US20100034803A1
公开(公告)日：2010-02-11
申请号：US11993553
申请日：2006-10-02
申请人： Hirobumi Senga , Zhongchao Han , Dingfang Cai , Li Li
发明人： Hirobumi Senga , Zhongchao Han , Dingfang Cai , Li Li
IPC分类号： A61K38/48
CPC分类号： C12N5/0647 , A61K38/00 , C12N5/0623 , C12N5/0692 , C12N9/6418 , C12N2533/56
摘要： The present invention provides an activating agent of stem cells and/or progenitor cells comprising a thrombin-like enzyme which can be used in regenerative medicine, and particularly in regenerative medicine utilizing self-regeneration, acting promptly and moderately depending on the state of advancement and the degree of injured organs and/or tissues to which regenerative medicine is applied, with few or no side effects. The present invention also provides a method for activating stem cells and/or progenitor cells in an animal comprising the step of administering to the animal an effective amount of a thrombin-like enzyme and use of the thrombin-like enzyme for activating stem cells and/or progenitor cells.
摘要翻译： 本发明提供一种干细胞和/或祖细胞的活化剂，其包含可用于再生医学中的凝血酶样酶，特别是在利用自我再生的再生医学中，其取决于进展状态及时和适度地起作用， 使用再生药物的受伤器官和/或组织的程度很少或没有副作用。 本发明还提供了一种用于激活动物中的干细胞和/或祖细胞的方法，包括向动物施用有效量的凝血酶样酶和使用凝血酶样酶来激活干细胞和/ 或祖细胞。
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