公开(公告)号：US20140370618A1

公开(公告)日：2014-12-18

申请号：US14336723

申请日：2014-07-21

申请人： Hiromi TAKENAKA ,  Yoshihito YOSHIDA ,  Katsunori HORII ,  Makio FURUICHI ,  Hirotaka YAGI ,  Jou AKITOMI ,  Mineko YAMAGUCHI ,  Shintarou KATOU ,  Kensaku NISHIKATA ,  Iwao WAGA

发明人： Hiromi TAKENAKA ,  Yoshihito YOSHIDA ,  Katsunori HORII ,  Makio FURUICHI ,  Hirotaka YAGI ,  Jou AKITOMI ,  Mineko YAMAGUCHI ,  Shintarou KATOU ,  Kensaku NISHIKATA ,  Iwao WAGA

IPC分类号： G01N33/68 ,  C12N15/115

CPC分类号： G01N33/6854 ,  C12N15/115 ,  C12N2310/16 ,  G01N33/5308

摘要： The present invention is to provide a nucleic acid molecule having a binding affinity to a rodent-derived IgG antibody, which can be prepared easier than an antibody and has a binding affinity equivalent or superior to that of an antibody, a binder using the nucleic acid molecule, a detection reagent, and a detection kit. The nucleic acid molecule of the present invention has a binding affinity to a rodent-derived IgG antibody and has a dissociation constant of 1 μM or less. The binder for a rodent-derived IgG antibody of the present invention includes the nucleic acid molecule of the present invention. The detection reagent for detecting a rodent-derived IgG antibody of the present invention includes the binder for a rodent-derived IgG antibody of the present invention. The detection kit for detecting a rodent-derived IgG antibody of the present invention includes the detection reagent for detecting a rodent-derived IgG antibody of the present invention.

摘要翻译： 本发明提供一种对啮齿动物IgG抗体具有结合亲和力的核酸分子，其可以比抗体更容易制备并具有与抗体相当或优于其抗体的结合亲和力，使用该核酸的粘合剂 分子，检测试剂和检测试剂盒。 本发明的核酸分子与啮齿动物IgG抗体具有结合亲和力，解离常数为1μM以下。 本发明的啮齿动物IgG抗体的粘合剂包括本发明的核酸分子。 用于检测本发明的啮齿动物IgG抗体的检测试剂包括本发明的啮齿动物IgG抗体的粘合剂。 用于检测本发明的啮齿动物IgG抗体的检测试剂盒包括用于检测本发明的啮齿动物的IgG抗体的检测试剂。