Human T cell-engrafted mouse, method for developing same and use thereof
    1.
    发明授权
    Human T cell-engrafted mouse, method for developing same and use thereof 失效
    人T细胞移植小鼠,其开发方法及其应用

    公开(公告)号:US06627792B2

    公开(公告)日:2003-09-30

    申请号:US09429110

    申请日:1999-10-28

    IPC分类号: A01K6700

    CPC分类号: A01K67/0271

    摘要: The present invention provides a method for developing a human T cell-engrafted mouse, which includes transplanting a human-derived bone tissue into an inbred line mouse deficient in immune cells, and a human T cell-engrafted mouse obtainable by the method. The present invention also provides a method for preparing an HIV-infected mouse model, which includes infecting the human T cell-engrafted mouse with HIV, and an HIV-infected mouse model obtainable by the method.

    摘要翻译: 本发明提供了一种开发人T细胞移植小鼠的方法,其包括将人衍生的骨组织移植到免疫细胞缺陷的近交系小鼠中,以及通过该方法获得的人T细胞移植小鼠。 本发明还提供了一种制备HIV感染的小鼠模型的方法,其包括用HIV感染人T细胞移植的小鼠,以及通过该方法可获得的HIV感染的小鼠模型。

    Digital scintillation camera system with correction for analog
scintillation camera system characteristics
    2.
    发明授权
    Digital scintillation camera system with correction for analog scintillation camera system characteristics 失效
    数字闪烁摄像机系统具有校正模拟闪烁摄像机系统的特点

    公开(公告)号:US4982327A

    公开(公告)日:1991-01-01

    申请号:US793767

    申请日:1985-11-01

    IPC分类号: A61B6/00 G01T1/164

    摘要: In a digital scintillation camera system, image data representing an radioisotope distribution is detected by a scintillation camera and is then digitized and converted to a video signal. The video signal is processed in a video imager to produce a diagnostic image on a film. A count-to-grey-level converter is arranged to convert a radiation count of diagnostic image data to a grey-level. A count-to-grey-level conversion table is accessed in the converter. The conversion table includes a correction component for obtaining the same count-density characteristics of a film as in a conventional analog scintillation camera system.

    摘要翻译: 在数字闪烁照相机系统中,通过闪烁照相机检测表示放射性同位素分布的图像数据,然后被数字化并转换为视频信号。 视频信号在视频成像器中处理以在胶片上产生诊断图像。 计数到灰度级转换器被布置成将诊断图像数据的辐射计数转换为灰度级。 在转换器中访问计数到灰度级的转换表。 转换表包括用于获得与常规模拟闪烁照相机系统相同的膜的相同计数密度特性的校正组件。

    Emission computed tomography apparatus
    3.
    发明授权
    Emission computed tomography apparatus 失效
    发射计算机断层摄影仪

    公开(公告)号:US4698506A

    公开(公告)日:1987-10-06

    申请号:US823203

    申请日:1986-01-28

    申请人: Yutaka Fujiki

    发明人: Yutaka Fujiki

    摘要: An emission computed tomography apparatus comprises a patient couch on which a subject on the dosage of rodioisotope (RI) lies and a two-dimensional position detector for collecting radioisotope distribution data in the subject at various rotation positions while rotating around the subject and the patient couch in order to obtain a tomogram image of the RI distribution in the subject. In order to eliminate a false image (artifact) on the tomogram image resulting form unequal detection characteristics in the position detector, the patient couch is traveled in one direction of the coordinate systems every time the position detector is rotated by a given angle. One position signal from the position detector is corrected in response to the traveling length of the patient couch. An artifact-free tomogram image of the RI distribution is obtained on the basis of the corrected position signal and another position signal from the position detector.

    摘要翻译: 发射计算机断层摄影装置包括患者坐在其上的受试者的位置上的啮齿动物同位素(RI)的剂量,以及二维位置检测器,用于在旋转周围的各个旋转位置收集患者的放射性同位素分布数据,同时围绕被检者和患者床 以获得对象中的RI分布的断层图像。 为了消除在位置检测器中形成不相等的检测特征的断层图像上的伪图像(伪影),每当位置检测器旋转给定的角度时,患者床沿着坐标系的一个方向行进。 来自位置检测器的一个位置信号响应于患者沙发的行进长度被校正。 基于校正的位置信号和来自位置检测器的另一位置信号,获得RI分布的无伪影层析图像。