公开(公告)号：US20230312837A1

公开(公告)日：2023-10-05

申请号：US18208029

申请日：2023-06-09

Applicant: Hoffmann-La Roche Inc.

Inventor： Floriane Bahuon ,  Jean Coudane ,  Vincent Darcos ,  Benjamin Nottelet ,  Sulabh Pravinchandra Patel ,  Gregoire Schwach

IPC: C08G81/00 ,  A61K9/00 ,  A61K45/06

CPC classification number: C08G81/00 ,  A61K9/0051 ,  A61K45/06

Abstract: Disclosed herein are novel copolymers of poly(ε-caprolactone) (PCL) and polydopamine (PDA), optionally further comprising a PEG chain, methods for making them as well as their use in pharmaceutical preparations, especially implants or in situ gelling depots, for the treatment of ocular disorders or eye diseases.