专利检索 ap:("Holger MONENSCHEIN" OR "Sean MURPHY" OR "Scott OLSEN" OR "Natasha O'ROURKE" OR "Holly REICHARD" OR "Melinda DAVIS" OR "Betty LAM" OR "TAKEDA PHARMACEUTICAL COMPANY LIMITED") AND inv:"Betty LAM" 第 1 页

1.

发明申请
AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES 有权

公开(公告)号：US20230028114A1

公开(公告)日：2023-01-26

申请号：US17753803

申请日：2020-09-15

申请人： Holger MONENSCHEIN , Sean MURPHY , Scott OLSEN , Natasha O'ROURKE , Holly REICHARD , Melinda DAVIS , Betty LAM , TAKEDA PHARMACEUTICAL COMPANY LIMITED

发明人： Holger MONENSCHEIN , Sean MURPHY , Scott OLSEN , Natasha O'ROURKE , Holly REICHARD , Melinda DAVIS , Betty LAM

IPC分类号： A61K31/5025 , C07D471/04

摘要： Disclosed are compounds of Formula (1) and pharmaceutically acceptable salts thereof, wherein α, β, n, R4, R5, R6, R8, R9, R10, R11, X1, X2, X3 and X7 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula (1), to pharmaceutical compositions comprising them, and to their use for treating diseases, disorders, and conditions associated with GPR139.