专利检索 ap:("Horizon Therapeutics USA, Inc.") AND inv:"Jacob Hartman" 第 1 页

1.

发明授权
Variant forms of urate oxidase and use thereof 有权

公开(公告)号：US11781119B2

公开(公告)日：2023-10-10

申请号：US17724091

申请日：2022-04-19

申请人： Horizon Therapeutics USA, Inc.

发明人： Jacob Hartman , Simona Mendelovitz

IPC分类号： A61K38/44 , A61K47/60 , C12N9/06

CPC分类号： C12N9/0048 , A61K38/44 , A61K47/60 , C12N9/0046 , C12Y107/03003

摘要： Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.

2.

发明授权
Variant forms of urate oxidase and use thereof 有权

公开(公告)号：US11345899B2

公开(公告)日：2022-05-31

申请号：US16911074

申请日：2020-06-24

申请人： Horizon Therapeutics USA, Inc.

发明人： Jacob Hartman , Simona Mendelovitz

IPC分类号： A61K38/44 , A61K47/60 , A61P3/12 , A61P9/06 , A61P3/00 , A61P43/00 , C12N9/06

摘要： Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidase are described.