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公开(公告)号:US20070154390A1
公开(公告)日:2007-07-05
申请号:US11449764
申请日:2006-06-09
申请人: Huang Chien Liang , Hsin-Ell Wang , Chin-I Lin , Shian-Jy Wang
发明人: Huang Chien Liang , Hsin-Ell Wang , Chin-I Lin , Shian-Jy Wang
CPC分类号: A61K51/065
摘要: A nuclear molecular imaging contrast agent. The nuclear imaging contrast agent comprises a polymer according to the structure of wherein, P is and 1 is not less than 1; D is a C3-30 dendritic moiety having a plurality of oxygen residue; Z is a C3-20 moiety having a plurality of functional groups, wherein the functional groups comprise carbonyl, carboxyl, amine, ester, amide, or chelate group; L is a radioisotope or analyte-specific moiety ; m is not less than two ; and at least one X is an analyte-specific moiety; the other X can be hydrogen atom.
摘要翻译: 核分子成像造影剂。 核成像造影剂包含根据其结构的聚合物,其中P为1且不小于1; D是具有多个氧残基的C3-30树枝状部分; Z是具有多个官能团的C3-20部分,其中官能团包括羰基,羧基,胺,酯,酰胺或螯合基团; L是放射性同位素或分析物特异性部分; m不小于2; 并且至少一个X是分析物特异性部分; 另外X可以是氢原子。