公开(公告)号：US20140039040A1

公开(公告)日：2014-02-06

申请号：US14057935

申请日：2013-10-18

Applicant: I-SHOU UNIVERSITY

Inventor： Ping-Heng Tan

IPC: A61K31/713

CPC classification number: A61K31/713 ,  A61K9/0019

Abstract: An analgesic medication includes an oligonucleotide being a double strand RNA comprising 18 to 70 base pairs, and a pharmaceutical acceptable vehicle for delivering the said oligonucleotide into cells, wherein a dosage of the oligonucleotide in the analgesic is 50 μg to 200 μg/kg per time, and the pharmaceutical acceptable vehicle is selected from a group of polyethyleneimine, lipofectamine and iFect.

Abstract translation: 止痛药包括含有18〜70碱基对的双链RNA的寡核苷酸，以及用于将所述寡核苷酸递送到细胞中的药物可接受载体，其中所述镇痛剂中的寡核苷酸的剂量为每次50ug至200ug / kg ，并且药物可接受的载体选自聚乙烯亚胺，脂质体和iFect组。

公开(公告)号：US09216190B2

公开(公告)日：2015-12-22

申请号：US14057935

申请日：2013-10-18

Applicant: I-SHOU UNIVERSITY

Inventor： Ping-Heng Tan

IPC: A61K31/713 ,  A61K9/00

CPC classification number: A61K31/713 ,  A61K9/0019

Abstract: An analgesic medication includes an oligonucleotide being a double strand RNA comprising 18 to 70 base pairs, and a pharmaceutical acceptable vehicle for delivering the said oligonucleotide into cells, wherein a dosage of the oligonucleotide in the analgesic is 50 μg to 200 μg/kg per time, and the pharmaceutical acceptable vehicle is selected from a group of polyethyleneimine, lipofectamine and iFect.

Abstract translation: 镇痛药包括含有18〜70个碱基对的双链RNA的寡核苷酸，以及用于将所述寡核苷酸递送到细胞中的药物可接受载体，其中所述镇痛剂中的寡核苷酸的剂量为每次50μg至200μg/ kg ，并且药物可接受的载体选自聚乙烯亚胺，脂质体和iFect组。