公开(公告)号：US09645138B2

公开(公告)日：2017-05-09

申请号：US14769550

申请日：2014-02-25

申请人： IMABIOTECH

发明人： Grégory Hamm ,  Jonathan Stauber

IPC分类号： G01N33/50 ,  A61K49/00

CPC分类号： G01N33/5035 ,  A61K49/0008 ,  G01N33/5082

摘要： The invention relates to a method for evaluating whether a molecule of interest binds or is incorporated in at least one target tissue, comprising visualizing and comparing the distribution of the molecule of interest and of at least one control compound within the target tissue or on the target tissue surface of at least one animal that has previously received the molecule of interest and/or the control compound. Advantageously, the distribution of the molecule of interest is visualized and compared with the distribution of positive and negative compounds using mass spectrometry imaging on the surface of the target tissue.