公开(公告)号：US20240002503A1

公开(公告)日：2024-01-04

申请号：US18249966

申请日：2021-10-20

Applicant: IMMUNE-ONC THERAPEUTICS, INC.

Inventor： Maria Jose COSTA ,  Ryan STAFFORD ,  Krista MCCUTCHEON ,  Jing-Tyan MA ,  Kyu Hee HONG ,  Hongyu TIAN ,  An SONG ,  X. Charlene LIAO

IPC: C07K16/28 ,  C12N15/63 ,  G01N33/574 ,  A61P35/00 ,  A61K39/00 ,  C12N5/078

CPC classification number: C07K16/2803 ,  C12N15/63 ,  G01N33/574 ,  A61P35/00 ,  A61K39/4631 ,  A61K39/461 ,  C12N5/0634 ,  C07K2317/24 ,  C07K2317/31

Abstract: The present disclosure provides anti-LILRB2 antibodies or antigen-binding fragments thereof, anti-LILRB2 chimeric antigen receptor protein, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.