公开(公告)号：US12187787B2

公开(公告)日：2025-01-07

申请号：US16982575

申请日：2019-02-26

Applicant: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY

Inventor： Hyung Joo Kwon ,  Te Ha Kim ,  Dong Bum Kim

IPC: C07K16/12 ,  A61K39/00 ,  A61P31/04

Abstract: The present invention relates to in a monoclonal antibody produced by CpG-DNA, or a functional fragment thereof, the monoclonal antibody, or functional fragment thereof, characterized in that it comprises polypeptide sequence selected from the group consisting of the following polypeptide sequences a heavy chain comprising a complementarity determining region 1 (CDR 1) amino acid sequence consisting of the sequence of SEQ ID NO: 1, a CDR2 consisting of the sequence of SEQ ID NO: 2 and a CDR 3 consisting of the sequence of SEQ ID NO: 3; and a light chain comprising CDR1 amino acid sequence consisting of the sequence of SEQ ID NO: 4, a CDR2 consisting of the sequence of SEQ ID NO: 5 and a CDR 3 consisting of the sequence of SEQ ID NO: 6 and a use of the same.