公开(公告)号：US20160067469A1

公开(公告)日：2016-03-10

申请号：US14889808

申请日：2014-05-02

申请人： INDUSTRY-ACA-DEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

发明人： Hyung Il JUNG ,  Hui Suk YANG ,  Su Yong KIM

IPC分类号： A61M37/00 ,  C09D101/08 ,  B29C41/08

CPC分类号： A61M37/0015 ,  A61K9/5089 ,  A61M2037/0046 ,  A61M2037/0053 ,  B29C41/085 ,  B29K2995/0056 ,  B29L2031/7544 ,  C09D101/08

摘要： The present invention relates to a method for manufacturing a microstructure, the method comprising the steps of: (a) preparing a viscous composition on a lower substrate; and (b) applying centrifugal force to the viscous composition to induce extension of the viscous composition, thereby manufacturing a microstructure. According to the present invention, (i) a microstructure having a micro-unit diameter and sufficient effective length and hardness is provided; (ii) any process that may destroy activation of a drug or cosmetic component, such as high-temperature treatment, organic solvent treatment, etc., is avoided; (iii) loss resulting from contact and separation is reduced; (iv) the limitation of aspect ratio of the manufactured microstructure is overcome; (v) the limitation of yield resulting from flatness is overcome; and (vi) microstructures of various shapes can be manufactured.

摘要翻译： 本发明涉及微结构的制造方法，该方法包括以下步骤：（a）在下基板上制备粘性组合物; 和（b）将离心力施加到粘性组合物以引起粘性组合物的延伸，从而制造微结构。 根据本发明，（i）提供具有微单位直径和足够的有效长度和硬度的微结构; （ii）避免可能破坏药物或化妆品成分的活化的任何方法，如高温处理，有机溶剂处理等; （iii）接触和分离造成的损失减少; （iv）克服制造的微结构的纵横比的限制; （v）克服平整度产生的收益的限制; 和（vi）可以制造各种形状的微结构。