专利检索 ap:("INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY" OR "KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY") AND inv:"Tae Hyun Park" 第 1 页

1.

发明授权
Pharmaceutical composition containing DUSP1 inhibitor 有权

公开(公告)号：US11147807B2

公开(公告)日：2021-10-19

申请号：US16603993

申请日：2018-02-28

申请人： INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

发明人： Seong Eon Ryu , Tae Hyun Park , Kwang Hwan Lee , Ju Seop Kang , Shin Hee Kim , Kyoung Tae Nam , Hyeon Kyu Lee

IPC分类号： A61K31/47 , A61P25/24 , A61P35/00

摘要： The present invention relates to a pharmaceutical composition comprising a DUSP1 inhibitor. The pharmaceutical composition comprising the DUSP1 inhibitor according to the present invention can solve the problems of inhibitors that target the active site because it inhibits DUSP1 by an allosteric inhibitory mechanism, and is effective for preventing or treating diseases involving DUSP1 enzymes, for example, a cancer such as a liver cancer, a breast cancer and a pancreatic cancer, a hepatitis C, and a depression. In particular, the DUSP1 inhibitor according to the present invention is very effective in treating a depression because it directly acts on neuronal growth.