公开(公告)号：US10286101B2

公开(公告)日：2019-05-14

申请号：US15102541

申请日：2014-12-10

申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ,  UNIVERSITÉ PARIS DIDEROT—PARIS 7 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  UNIVERSITÉ PARIS XIII PARIS-NORD ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE PARIS ,  UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6)

发明人： Ludwik Leibler ,  Anne Meddahipelle ,  Didier Letourneur ,  Alba Marcellan-Parisot

IPC分类号： A61L24/02 ,  A61L26/00 ,  A61L24/00 ,  A61L24/08

摘要： The present invention relates to methods for adhering tissue surfaces and materials and biomedical uses thereof. In particular the present invention relates to a method for adhering a first tissue surface to a second tissue surface in a subject in need thereof, comprising the steps of adsorbing a layer of nanoparticles on at least one of the tissue surfaces, and approximating the surfaces for a time sufficient for allowing the surfaces to adhere to each other. The present invention also relates to a method for adhering a material to a biological tissue in a subject in need thereof, comprising the steps of adsorbing a layer of nanoparticles on the surface of the material and/or the biological tissue and approximating the material and the biological tissue for a time sufficient for allowing the material and the biological tissue to adhere to each other.