专利检索 ap:("INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)" OR "UNIVERSITE PAUL SABATIER TOULOUSE III" OR "CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE") AND inv:"Anne Montfort" 第 1 页

1.

发明授权
Methods and pharmaceutical compositions for enhancing CD8+ T cell-dependent immune responses in subjects suffering from cancer 有权

公开(公告)号：US11078277B2

公开(公告)日：2021-08-03

申请号：US16074555

申请日：2017-02-01

申请人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE PAUL SABATIER TOULOUSE III , CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE

发明人： Thierry Levade , Bruno Segui , Florie Bertrand , Julia Rochotte , Anne Montfort , Nathalie Andrieu-Abadie , Celine Colacios Viatge , Nicolas Meyer

IPC分类号： A61K48/00 , A61P35/00 , C12N15/86 , C07K16/28 , A61K38/46 , A61K31/713 , A61K39/00 , A61K9/127 , C12N9/16 , G01N33/569

摘要： The present invention relates to methods and pharmaceutical compositions for enhancing CD8+ T cell-dependent immune responses in subjects suffering from cancer. In particular, the present invention relates to a method of enhancing the CD8+ T cell-dependent immune response in a subject suffering from cancer comprising administering to the subject a therapeutically effective amount of an agent capable of increasing intra-tumoral ceramide content.