公开(公告)号：US11589838B2

公开(公告)日：2023-02-28

申请号：US16980875

申请日：2019-03-15

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  CENTRE LÉON-BÉRARD ,  UNIVERSITÉ CLAUDE BERNARD LYON 1

发明人： Kazuhiro Matsui ,  William Apoutou N'Djin ,  Rémi Souchon

IPC分类号： A61B8/08 ,  A61B8/00

摘要： This method, for determining the local intensity (I0) of an acoustic field propagating in a target region of a soft solid, at a position located within said target region, includes at least the following steps: determining (102) a value of an ultrasound attenuation coefficient (α) of the soft body in the target region; determining (104) a value of the shear modulus (μ) of the soft body in the target region; determining (106) a value of the speed of sound (c) in the target region of the soft body; and building (110), with the values determined in steps a), b) and c), a viscoelastic model (M) of a steady-state displacement induced by an acoustic field having a time invariant shape or a viscoelastic model of a difference between two steady-state displacements induced by an acoustic field having a time invariant shape. Moreover, this method also includes the following steps: applying (112) to the target region the acoustic field emitted by an ultrasound source, for a duration such that the acoustic field induces a steady-state localized deformation (Formula (I)) of the soft body in the target region; measuring (114) at least one steady state displacement induced by the acoustic field at a given position in the target region; and computing (116) the amplitude of the intensity of the acoustic field at said given position by inverting the viscoelastic model (M) at said given position, for the displacement(s) measured at step f).