公开(公告)号：US20210100821A1

公开(公告)日：2021-04-08

申请号：US16971179

申请日：2019-02-26

申请人： INTAS PHARMACEUTICALS LTD.

发明人： Aditya PATEL ,  Kerul PATEL ,  Dhaval DADHANIYA

IPC分类号： A61K31/675 ,  A61K9/19 ,  A61K47/26

摘要： This present invention relates to a stable lyophilized composition of Cyclophosphamide. The said stable lyophilized composition of Cyclophosphamide provides an improved moisture content than the lyophilized Cyclophosphamide compositions obtained by the conventional lyophilization method. Further, the invention relates to a process for preparation of the said stable lyophilized composition of Cyclophosphamide, wherein the said process comprises controlled lyophilization with freezing and annealing at a temperature above 0° C.