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公开(公告)号：US20190218219A1
公开(公告)日：2019-07-18
申请号：US16244796
申请日：2019-01-10
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines
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公开(公告)号：US20160194326A1
公开(公告)日：2016-07-07
申请号：US15066962
申请日：2016-03-10
Applicant: Intra-Cellular Therapies, Inc.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
CPC classification number: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycl fused gamma-carbolines.
Abstract translation: 本发明提供了制备取代的杂环稠合的γ-咔啉的方法，可用于制备它们的中间体和用于制备这种中间体的方法和这种杂环稠合的γ-咔啉。
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公开(公告)号：US20200087305A1
公开(公告)日：2020-03-19
申请号：US16594603
申请日：2019-10-07
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines.
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Patent Agency Ranking
公开(公告)号：US20180044337A1
公开(公告)日：2018-02-15
申请号：US15660762
申请日：2017-07-26
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
CPC classification number: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycl fused gamma-carbolines.
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![PROCESS FOR PREPARING INTERMEDIATES FOR 1-(4-FLUOROPHENYL)-4-((6bR,10aS)-3-METHYL-2,3,6b,9,10,10a-HEXAHYDRO-1H-PYRIDO[3’,4’:4,5]PYRROLO[1,2,3-de]QUINOXALIN-8(7H)-YL)BUTAN-1-ONE](/abs-image/US/2025/03/27/US20250101022A1/abs.jpg.150x150.jpg)
公开(公告)号：US20250101022A1
公开(公告)日：2025-03-27
申请号：US18905607
申请日：2024-10-03
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, such as the compound of Formula 1J, as shown below, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines, and as further defined herein:
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公开(公告)号：US20220332716A1
公开(公告)日：2022-10-20
申请号：US17808836
申请日：2022-06-24
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycl fused gamma-carbolines.
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公开(公告)号：US20190292185A1
公开(公告)日：2019-09-26
申请号：US16439361
申请日：2019-06-12
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines.
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公开(公告)号：US20140364609A1
公开(公告)日：2014-12-11
申请号：US14323545
申请日：2014-07-03
Applicant: INTRA-CELLULAR THERAPIES, INC.
Inventor： John Charles TOMESCH , Peng LI , Wei YAO , Qiang ZHANG , James David BEARD , Andrew S. THOMPSON , Hua CHENG , Lawrence P. WENNOGLE
IPC: C07D471/16 , C07D471/04
CPC classification number: C07D471/16 , C07D471/04
Abstract: The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines.
Abstract translation: 本发明提供了制备取代的杂环稠合的γ-咔啉的方法，可用于制备它们的中间体和制备这种中间体的方法和这种杂环稠合的γ-咔啉。
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