公开(公告)号：US20230323300A1

公开(公告)日：2023-10-12

申请号：US18022415

申请日：2021-08-17

申请人： IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)

发明人： Eun Jung BAEK ,  Eun MI LEE ,  So Yeon HAN ,  Won-Seok CHOI ,  Jang Han LEE ,  Hyo Sang LEE

IPC分类号： C12N5/078 ,  C12M3/06

CPC分类号： C12N5/0641 ,  C12M27/14 ,  C12N2527/00 ,  C12N2506/11

摘要： The present invention relates to a method for in vitro production of red blood cells. The method for in vitro production of red blood cells, according to the present invention, specifies, by cell size, the maturation step of cells exhibiting optimal effects in an agitation-type culture, so that even if an expert does not always identify cell shape, automated processes of culturing are possible, and thus automation in bioreactors is possible in the mass-production of uniform quality and red blood cells.