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公开(公告)号：US08618166B2
公开(公告)日：2013-12-31
申请号：US13540319
申请日：2012-07-02
申请人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/232
CPC分类号： A61K31/202 , A61K9/48 , A61K31/222 , A61K31/232 , A61K31/40 , A61K31/505 , A61K31/74 , A61K45/06 , A61K47/22 , A61K47/26 , A61K47/34 , A61K2300/00
摘要： The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
摘要翻译： 本公开尤其涉及用二十碳五烯酸乙酯处理混合型血脂异常的方法。
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2.发明授权公开(公告)号：US08557799B2
公开(公告)日：2013-10-15
申请号：US13403699
申请日：2012-02-23
申请人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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公开(公告)号：US08415335B2
公开(公告)日：2013-04-09
申请号：US13349157
申请日：2012-01-12
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US20130017256A1
公开(公告)日：2013-01-17
申请号：US13623450
申请日：2012-09-20
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K31/232 , A61K9/48 , A61P3/06
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
摘要翻译： 在各种实施方案中，本发明提供了治疗和/或预防心血管相关疾病，特别是血脂治疗方法的方法，其包括向有需要的受试者施用包含二十碳五烯酸或其衍生物的药物组合物。
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公开(公告)号：US08324195B2
公开(公告)日：2012-12-04
申请号：US13349150
申请日：2012-01-12
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
摘要翻译： 在各种实施方案中，本发明提供了治疗和/或预防心血管相关疾病，特别是血脂治疗方法的方法，其包括向有需要的受试者施用包含二十碳五烯酸或其衍生物的药物组合物。
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公开(公告)号：US08314086B2
公开(公告)日：2012-11-20
申请号：US13284408
申请日：2011-10-28
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US08293728B2
公开(公告)日：2012-10-23
申请号：US13349153
申请日：2012-01-12
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US20120108659A1
公开(公告)日：2012-05-03
申请号：US13349153
申请日：2012-01-12
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K31/232 , A61P7/00
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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9.发明授权Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy 有权用于降低甘油三酯的组合物和方法，而不增加受试者中伴随的他汀类药物治疗的LDL-C水平公开(公告)号：US08455472B2
公开(公告)日：2013-06-04
申请号：US12815569
申请日：2010-06-15
申请人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
CPC分类号： A61K31/232 , A61K9/48 , A61K31/202 , A61K31/366 , A61K31/40 , A61K31/505 , A61K2300/00
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
摘要翻译： 在各种实施方案中，本发明提供了在有需要的受试者中治疗和/或预防心血管相关疾病的组合物和方法。
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公开(公告)号：US08445013B2
公开(公告)日：2013-05-21
申请号：US13614129
申请日：2012-09-13
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K9/48 , A61K31/232 , A61P3/06 , A61P9/00
CPC分类号： A61K31/202 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/232 , A61K45/06
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
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