Anti-human interleukin-20 antibodies
    9.
    发明授权
    Anti-human interleukin-20 antibodies 失效
    抗人白细胞介素20抗体

    公开(公告)号:US08287861B2

    公开(公告)日:2012-10-16

    申请号:US12601164

    申请日:2009-06-30

    IPC分类号: A61K39/395 A61K39/00 C12N5/07

    摘要: Anti-human IL20 monoclonal antibodies that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes in one or more species, including humans, are described, as well as antigen-binding molecules such as, e.g., antigen-binding antibody fragments, antibody derivatives, and multi-specific molecules designed or derived from such antibodies, and methods or producing such antibodies or other antigen-binding molecules. Such antibodies or other antigen-binding molecules can be used for treating various diseases and disorders, including autoimmune or inflammatory diseases or disorders.

    摘要翻译: 本发明描述了可以降低IL20介导的包括人在内的一种或多种物种中的IL20R1 / IL20R2和IL22R1 / IL20R2受体复合物的IL20介导的活化的抗人IL20单克隆抗体,以及抗原结合分子,例如抗原结合 抗体片段,抗体衍生物和设计或衍生自该抗体的多特异性分子,以及方法或产生此类抗体或其他抗原结合分子。 这样的抗体或其它抗原结合分子可用于治疗各种疾病和病症,包括自身免疫性或炎性疾病或病症。

    ANTI-HUMAN INTERLEUKIN-20 ANTIBODIES
    10.
    发明申请
    ANTI-HUMAN INTERLEUKIN-20 ANTIBODIES 审中-公开
    抗人类白细胞抗原-2抗体

    公开(公告)号:US20130039923A1

    公开(公告)日:2013-02-14

    申请号:US13606642

    申请日:2012-09-07

    摘要: Anti-human IL20 monoclonal antibodies that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes in one or more species, including humans, are described, as well as antigen-binding molecules such as, e.g., antigen-binding antibody fragments, antibody derivatives, and multi-specific molecules designed or derived from such antibodies, and methods or producing such antibodies or other antigen-binding molecules. Such antibodies or other antigen-binding molecules can be used for treating various diseases and disorders, including autoimmune or inflammatory diseases or disorders.

    摘要翻译: 本发明描述了可以降低IL20介导的包括人在内的一种或多种物种中的IL20R1 / IL20R2和IL22R1 / IL20R2受体复合物的IL20介导的活化的抗人IL20单克隆抗体,以及抗原结合分子,例如抗原结合 抗体片段,抗体衍生物和设计或衍生自该抗体的多特异性分子,以及方法或产生此类抗体或其他抗原结合分子。 这样的抗体或其它抗原结合分子可用于治疗各种疾病和病症,包括自身免疫性或炎性疾病或病症。