专利检索 ap:("Imber Montes" OR "Hieu Pham" OR "Lan Nguyen" OR "Vinh Diep" OR "Emanuele Burattini" OR "Carlo Severi" OR "Eric Neisor" OR "Anne Perez" OR "Jean-Luc Thuillard" OR "Yves Guyon-Gellin" OR "Craig Bentzen") AND inv:"Carlo Severi" 第 1 页

1.

发明申请
1,1-and 1,2-Bisphosphonates as apoliprotein e modulators 审中-公开
标题翻译： 1,1和1,2-二膦酸酯作为载脂蛋白e调节剂

公开(公告)号：US20060205692A1

公开(公告)日：2006-09-14

申请号：US10513552

申请日：2003-05-09

申请人： Imber Montes , Hieu Pham , Lan Nguyen , Vinh Diep , Emanuele Burattini , Carlo Severi , Eric Neisor , Anne Perez , Jean-Luc Thuillard , Yves Guyon-Gellin , Craig Bentzen

发明人： Imber Montes , Hieu Pham , Lan Nguyen , Vinh Diep , Emanuele Burattini , Carlo Severi , Eric Neisor , Anne Perez , Jean-Luc Thuillard , Yves Guyon-Gellin , Craig Bentzen

IPC分类号： A61K31/675 , A61K31/663 , C07F9/58 , C07F9/572 , C07F9/28

CPC分类号： C07F9/404 , C07F9/4025 , C07F9/572 , C07F9/5728 , C07F9/5765 , C07F9/58 , C07F9/59 , C07F9/6533

摘要： The present invention relates to methods of use 1,1- and 1,2-bisphosphonate compounds to modulate apolipoprotein E levels and use of such compounds in therapy, including cardiovascular and neurological disease states.

摘要翻译： 本发明涉及使用1,1-和1,2-二膦酸盐化合物调节载脂蛋白E水平和在治疗中使用这些化合物的方法，包括心血管和神经疾病状态。