公开(公告)号：US20210017492A1

公开(公告)日：2021-01-21

申请号：US17062170

申请日：2020-10-02

Applicant: Immatics US, Inc.

Inventor： Thorsten DEMBERG

IPC: C12N5/0783 ,  C07K16/28 ,  A61K35/17

Abstract: The present disclosure generally relates to methods of improving T cell homing to organs or tissues by utilizing compounds and compositions, for example, retinoic acid receptor agonists. In an aspect, the disclosure provides for organ-homing engineered T cells for treating diseases, associated compositions, and methods for preparing thereof.

公开(公告)号：US20200318068A1

公开(公告)日：2020-10-08

申请号：US16839881

申请日：2020-04-03

Applicant: Immatics US, Inc.

Inventor： Thorsten DEMBERG

IPC: C12N5/0783 ,  C07K16/28 ,  A61K35/17

Abstract: The present disclosure generally relates to methods of improving T cell homing to organs or tissues by utilizing compounds and compositions, for example, retinoic acid receptor agonists. In an aspect, the disclosure provides for organ-homing engineered T cells for treating diseases, associated compositions, and methods for preparing thereof.