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公开(公告)号:US12084430B2
公开(公告)日:2024-09-10
申请号:US18122323
申请日:2023-03-16
申请人: Incyte Corporation
发明人: Cooper Taylor , Yanran Ai , Chunhong He , Ke Zhang , Eddy W. Yue
IPC分类号: C07D401/14 , A61P35/00 , A61P35/02 , C07D471/14
CPC分类号: C07D401/14
摘要: The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.
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公开(公告)号:US20230295124A1
公开(公告)日:2023-09-21
申请号:US18122323
申请日:2023-03-16
申请人: Incyte Corporation
发明人: Cooper Taylor , Yanran Ai , Chunhong He , Ke Zhang , Zhitong Zheng , Eddy W. Yue
IPC分类号: C07D401/14
CPC分类号: C07D401/14
摘要: The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.
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