公开(公告)号：US20250066363A1

公开(公告)日：2025-02-27

申请号：US18813538

申请日：2024-08-23

Applicant: Incyte Corporation

Inventor： Joshua Hummel ,  Liana Hie ,  Jacob J. Lacharity ,  Xiaolei Li ,  Ding-Quan Qian ,  Xiaozhao Wang ,  Bo Wei

IPC: C07D473/18 ,  A61K31/496 ,  A61K31/522 ,  C07D471/04 ,  C07D487/04

Abstract: The present application provides bicyclic compounds that modulate the activity of diacylglycerol kinase (DGK), which are useful in the treatment of various diseases, including cancer.

公开(公告)号：US20230399342A1

公开(公告)日：2023-12-14

申请号：US18330623

申请日：2023-06-07

Applicant: Incyte Corporation

Inventor： Joshua Hummel ,  Liana Hie ,  Jacob J. Lacharity ,  Xiaolei Li ,  Sharada Manns ,  Ding-Quan Qian ,  Xiaozhao Wang ,  Bo Wei ,  Meizhong Xu

IPC: C07D513/14 ,  C07D487/14

CPC classification number: C07D513/14 ,  C07D487/14 ,  C07B2200/05

Abstract: The present application provides tricyclic triazolo compounds that modulate the activity of diacylglycerol kinase (DGK), which are useful in the treatment of various diseases, including cancer.