公开(公告)号：US11666655B2

公开(公告)日：2023-06-06

申请号：US16315360

申请日：2017-06-08

申请人： Indian Institute of Technology, Delhi

发明人： Anurag Singh Rathore ,  V. Haridas ,  Rohit Bansal ,  Soumili Chattopadhyay ,  Sameer Dhawan

IPC分类号： A61K47/60 ,  C08L101/00 ,  A61K39/395

CPC分类号： A61K47/60 ,  A61K39/39591 ,  C08L101/005

摘要： The present disclosure relates to a formulation including: a) a dendron of Formula I; b) at least one bio-therapeutic; c) at least one buffer; and d) at least one salt, wherein the bio-therapeutic to dendron molar ratio is in the range of 1:0.5-1:3. The dendron stabilizes the bio-therapeutic in the formulation at a temperature of up to 55° C.

公开(公告)号：US20200179523A1

公开(公告)日：2020-06-11

申请号：US16315360

申请日：2017-06-08

申请人： Indian Institute of Technology, Delhi

发明人： Anurag Singh Rathore ,  V. Haridas ,  Rohit Bansal ,  Soumili Chattopadhyay ,  Sameer Dhawan

IPC分类号： A61K47/60

摘要： The present disclosure relates to a formulation including: a) a dendron of Formula I; b) at least one bio-therapeutic; c) at least one buffer; and d) at least one salt, wherein the bio-therapeutic to dendron molar ratio is in the range of 1:0.5-1:3. The dendron stabilizes the bio-therapeutic in the formulation at a temperature of up to 55° C.