公开(公告)号：US20150135344A1

公开(公告)日：2015-05-14

申请号：US14491183

申请日：2014-09-19

Applicant: Indiana University Research and Technology Corporation

Inventor： Alfred Joseph Tector, III ,  Christopher Burlak

IPC: A01K67/027 ,  A61K35/407

CPC classification number: A01K67/0276 ,  A01K2227/108 ,  A01K2267/025 ,  A61K35/407

Abstract: The application provides methods of modulating platelet uptake by liver sinusoidal endothelial cells and of modulating thrombocytopenia. Transgenic pigs modified to bind fewer platelets are provided.

Abstract translation: 该应用提供了调节肝窦内皮细胞血小板摄取和调节血小板减少症的方法。 提供了修饰以结合较少血小板的转基因猪。

公开(公告)号：US09420770B2

公开(公告)日：2016-08-23

申请号：US14491183

申请日：2014-09-19

Applicant: Indiana University Research and Technology Corporation

Inventor： Alfred Joseph Tector, III ,  Christopher Burlak

IPC: G01N33/00 ,  A01K67/00 ,  A01K67/033 ,  A01K67/027 ,  A61K35/407

CPC classification number: A01K67/0276 ,  A01K2227/108 ,  A01K2267/025 ,  A61K35/407

Abstract: The application provides methods of modulating platelet uptake by liver sinusoidal endothelial cells and of modulating thrombocytopenia. Transgenic pigs modified to bind fewer platelets are provided.

Abstract translation: 该应用提供了调节肝窦内皮细胞血小板摄取和调节血小板减少症的方法。 提供了修饰以结合较少血小板的转基因猪。