公开(公告)号：US11707445B2

公开(公告)日：2023-07-25

申请号：US17226781

申请日：2021-04-09

Applicant: Indiana University Research and Technology Corporation

Inventor： Timothy William Corson ,  Rania Sulaiman

IPC: A61K31/353 ,  A61P27/02 ,  A61K39/395 ,  A61K31/343 ,  A61K31/335 ,  A61K39/00

CPC classification number: A61K31/353 ,  A61K31/335 ,  A61K31/343 ,  A61K39/39541 ,  A61P27/02 ,  A61K2039/505

Abstract: Compositions including the combination of cremastranone analogs and anti-angiogenic agents and the use of the compositions for targeting ocular angiogenesis such as seen in neovascular eye diseases are disclosed.

公开(公告)号：US20240082211A1

公开(公告)日：2024-03-14

申请号：US18512376

申请日：2023-11-17

Applicant: Indiana University Research and Technology Corporation

Inventor： Timothy William Corson ,  Rania Sulaiman

IPC: A61K31/353 ,  A61K9/00 ,  A61K9/06 ,  A61K31/192 ,  A61K31/423 ,  A61K39/395 ,  A61P27/02

CPC classification number: A61K31/353 ,  A61K9/0019 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/06 ,  A61K31/192 ,  A61K31/423 ,  A61K39/3955 ,  A61P27/02

Abstract: Methods of using compounds to inhibit ocular disease are disclosed herein. Methods are disclosed for inhibiting soluble epoxide hydrolase (sEH) for the treatment of ocular diseases, and in particular, retinopathy of prematurity (ROP) or diabetic retinopathy.

公开(公告)号：US20180353464A1

公开(公告)日：2018-12-13

申请号：US15780980

申请日：2016-11-18

Applicant: Indiana University Research and Technology Corporation

Inventor： Timothy William Corson ,  Rania Sulaiman

IPC: A61K31/353 ,  A61K39/395 ,  A61P27/02

CPC classification number: A61K31/353 ,  A61K31/335 ,  A61K31/343 ,  A61K39/39541 ,  A61K2039/505 ,  A61P27/02

Abstract: Compositions including the combination of cremastranone analogs and anti-angiogenic agents and the use of the compositions for targeting ocular angiogenesis such as seen in neovascular eye diseases are disclosed.

公开(公告)号：US20210228538A1

公开(公告)日：2021-07-29

申请号：US17226781

申请日：2021-04-09

Applicant: Indiana University Research and Technology Corporation

Inventor： Timothy William Corson ,  Rania Sulaiman

IPC: A61K31/353 ,  A61K31/343 ,  A61K31/335 ,  A61P27/02 ,  A61K39/395

Abstract: Compositions including the combination of cremastranone analogs and anti-angiogenic agents and the use of the compositions for targeting ocular angiogenesis such as seen in neovascular eye diseases are disclosed.

公开(公告)号：US20210228539A1

公开(公告)日：2021-07-29

申请号：US17226814

申请日：2021-04-09

Applicant: Indiana University Research and Technology Corporation

Inventor： Timothy William Corson ,  Rania Sulaiman

IPC: A61K31/353 ,  A61P27/02 ,  A61K9/00 ,  A61K31/423 ,  A61K39/395 ,  A61K31/192 ,  A61K9/06

Abstract: Methods of using compounds to inhibit ocular disease are disclosed herein. Methods are disclosed for inhibiting soluble epoxide hydrolase (sEH) for the treatment of ocular diseases, and in particular, wet age-related macular degeneration (AMD).

公开(公告)号：US20180228764A1

公开(公告)日：2018-08-16

申请号：US15889464

申请日：2018-02-06

Applicant: Indiana University Research and Technology Corporation

Inventor： Timothy William Corson ,  Rania Sulaiman

IPC: A61K31/353 ,  A61P27/02 ,  A61K9/00 ,  A61K9/06 ,  A61K39/395 ,  A61K31/192 ,  A61K31/423

CPC classification number: A61K31/353 ,  A61K9/0019 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/06 ,  A61K31/192 ,  A61K31/423 ,  A61K39/3955 ,  A61P27/02

Abstract: Methods of using compounds that inhibit soluble epoxide hydrolase (sEH) for the treatment of ocular diseases, and in particular, of wet age-related macular degeneration (AMD), are disclosed herein.