公开(公告)号：US20190000312A1

公开(公告)日：2019-01-03

申请号：US16062621

申请日：2016-12-20

Applicant: Indiana University Research and Technology Corporation

Inventor： Ping Situ ,  Carolyn Begley ,  Trefford L. Simpson

IPC: A61B3/09 ,  A61B3/00

Abstract: A method of determining a predisposition to contact lens discomfort in a patient is provided, comprising determining a detection threshold of the patient by delivering a cool mechanical stimulus to the cornea of the patient, optionally applying a series of cool mechanical stimuli to the cornea of the patient, and classifying the patient as being predisposed to contact lens discomfort if the detection threshold is at or below a cut-off value predetermined to be associated with predisposition to contact lens discomfort and/or the patient does not adapt to the series of cool mechanical stimuli.

公开(公告)号：US11317797B2

公开(公告)日：2022-05-03

申请号：US16062621

申请日：2016-12-20

Applicant: Indiana University Research and Technology Corporation

Inventor： Ping Situ ,  Carolyn Begley ,  Trefford L. Simpson

IPC: A61B3/09 ,  A61B3/00 ,  A61B3/02 ,  A61B5/00 ,  A61B3/10

Abstract: A method of determining a predisposition to contact lens discomfort in a patient is provided, comprising determining a detection threshold of the patient by delivering a cool mechanical stimulus to the cornea of the patient, optionally applying a series of cool mechanical stimuli to the cornea of the patient, and classifying the patient as being predisposed to contact lens discomfort if the detection threshold is at or below a cut-off value predetermined to be associated with predisposition to contact lens discomfort and/or the patient does not adapt to the series of cool mechanical stimuli.