公开(公告)号：US20140193871A1

公开(公告)日：2014-07-10

申请号：US14140627

申请日：2013-12-26

Applicant: Industrial Technology Research Institute

Inventor： Chang-Chieh CHEN ,  Hsin-Tzu Kuo ,  Yi-Te Chou ,  Chin-Chen Hsu ,  Shao-Wen Wu

IPC: C12P7/54 ,  C12P7/06

CPC classification number: C12P7/06 ,  C12P7/065 ,  C12P7/16 ,  C12P7/42 ,  C12P7/54 ,  Y02E50/10 ,  Y02E50/17

Abstract: At least one product chosen from acids and alcohols is produced by a microbial fermentation process comprising: providing a gaseous substrate and a liquid medium to a microorganism, wherein the liquid medium comprises lactic acid and/or salts thereof, and wherein the gaseous substrate comprises at least one carbon source chosen from CO and CO2, and allowing the microorganism to produce at least one product chosen from acids and alcohols.

Abstract translation: 通过微生物发酵方法产生选自酸和醇的至少一种产物，其包括：向微生物提供气态底物和液体培养基，其中所述液体培养基包含乳酸和/或其盐，并且其中所述气态底物包含 选自CO和CO 2的至少一种碳源，并允许微生物产生至少一种选自酸和醇的产物。

公开(公告)号：US20210198684A1

公开(公告)日：2021-07-01

申请号：US17135402

申请日：2020-12-28

Applicant: Industrial Technology Research Institute

Inventor： Chang-Chieh CHEN ,  Shao-I WU ,  Jo-Di CHIANG ,  Yu-Pei LIN ,  Wen-Chang LU

IPC: C12N15/82 ,  C12N1/12 ,  C12N15/113

Abstract: A method for increasing the yield of microalgae and the yield of a product produced by the microalgae is provided. The method includes performing a change procedure on CAM1 gene and/or calmodulin 1 encoded by the CAM1 gene in a microalga, such that a change occurs in a nucleotide and/or the nucleotide sequence of the CAM1 gene and/or an amino acid and/or the amino acid sequence of the calmodulin 1 encoded by the CAM1 gene in the microalga to obtain an altered microalga. The altered microalga has an altered CAM1 gene and/or an altered calmodulin 1. The altered microalga has a higher growth rate and a higher product production rate and/or yield than an unaltered microalga.

公开(公告)号：US20180265836A1

公开(公告)日：2018-09-20

申请号：US15923465

申请日：2018-03-16

Applicant: Industrial Technology Research Institute

Inventor： Chang-Chieh CHEN ,  Ming-Der BAI ,  Shao-I WU ,  Hsin-Tzu KUO ,  Wen-Chang LU ,  Hou-Peng WAN

IPC: C12N1/12 ,  C12N15/75 ,  C12N1/02

CPC classification number: C12N1/12 ,  C12N1/02 ,  C12N1/20 ,  C12N1/38 ,  C12N15/75 ,  C12R1/075

Abstract: The present disclosure provides a new mutant of Bacillus thuringiensis which is deposited under Accession number DSM 32419. The present disclosure also provides a method for manufacturing a growth promoter for promoting microalgal cell growth, including: (a) inoculating a mutant of Bacillus thuringiensis into a culturing medium to obtain a bacterial suspension, wherein the mutant of Bacillus thuringiensis is deposited under Accession number DSM 32419; (b) culturing the mutant of Bacillus thuringiensis in the bacterial suspension at least to a stationary phase to obtain a cultured medium of the mutant of Bacillus thuringiensis; and (c) performing a vacuum heating procedure on the cultured medium of the mutant of Bacillus thuringiensis to obtain the growth promoter for promoting microalgal cell growth, wherein the growth promoter for promoting microalgal cell growth contains active substances for promoting microalgal cell growth.